Advances in tacrine for Alzheimers disease

Alzheimers disease is a kind of neurodegenerative disease with insidious and progressive onset, which will affect the normal life of patients to varying degrees. At present, there is no specific drug that can completely cure Alzheimers disease, and there is still a long way to go in the treatment of the disease. In order to provide better ideas for the development of drugs to treat Alzheimers disease, people have speculated and verified a variety of pathogenesis of the disease as far as possible and developed targeted drugs on this basis. In addition to the need to develop drugs from multiple pathogenetic perspectives, it is also necessary to conduct longitudinal studies on one drug. Since tachrine is one of the drugs with great development potential, this paper will take Tachrine, a representative of cholinesterase inhibitors, as the main drug research object, analyze the structure and efficacy of various existing tachrine drugs, and try to provide the future development direction of Tachrine drug transformation.