新诊断的 2 型糖尿病患者中代谢综合征及其风险因素的患病率 - 一项基于医院的横断面研究

IF 16.4 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Accounts of Chemical Research Pub Date : 2024-07-26 DOI:10.4103/jfmpc.jfmpc_51_24

S. T. R. Krishna, Y. Bahurupi, Ravi Kant, Pradeep Aggarwal, Athulya V. Ajith

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引用次数: 0

摘要

摘要代谢综合征（MetS）会增加 2 型糖尿病（T2DM）患者发生脑血管意外和心血管疾病的几率。及早发现代谢综合征可采取适当的预防和治疗策略来降低风险。本研究旨在估算 MetS 及其风险因素在 T2DM 患者中的患病率。这项横断面研究调查了三级甲等医院新诊断出的 T2DM 患者中 MetS 及其组成部分的患病率。该研究于2022年1月至2022年12月进行，共纳入300名18岁以上的参与者，其中大多数为男性（55%，165人），并使用世界卫生组织（WHO）的STEPS问卷评估选定的风险因素。根据美国国家胆固醇教育计划（NCEP）成人治疗小组 III（ATP III）的标准，除血糖外，还评估了 MetS 的不同组成部分，即血清甘油三酯（TG）水平、血清高密度脂蛋白（HDL）水平、血压（BP）和腰围（WC）。数据分析包括数字变量的均值和标准差（SD），用非配对 t 检验比较均值；分类变量的百分比和比例，用卡方检验比较相关性。肥胖、高血压（HTN）、总胆固醇（TG）和高密度脂蛋白（HDL）的发病率分别为 64.0%（192 人）、45.7%（137 人）、46.0%（138 人）和 30%（90 人）。总体而言，MetS 的比例为 57%（170 人）。每周 150 分钟的适度活动、坐姿/躺姿、腹围、舒张压、总胆固醇和高密度脂蛋白与 MetS 有显著关联。 MetS 与新诊断的 T2DM 高度相关，肥胖是最常见的组成部分。

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Prevalence of metabolic syndrome and its risk factors among newly diagnosed type 2 diabetes mellitus patients – A hospital-based cross-sectional study

ABSTRACT Metabolic syndrome (MetS) raises the chance of cerebrovascular accidents and cardiovascular illness in type 2 diabetes mellitus (T2DM) individuals. Early identification of MetS allows for suitable prophylactic and treatment strategies to reduce the risks. To estimate the prevalence of MetS and its risk factors in T2DM individuals. This cross-sectional study investigated MetS and its component’s prevalence among newly diagnosed T2DM at the tertiary care hospital. The study was conducted from January 2022 to December 2022 and included 300 participants above 18 years, with most being men (55%, 165), and using the World Health Organization (WHO) STEPS questionnaire for assessing selected risk factors. Along with blood glucose, different components of MetS were assessed, that is serum triglyceride (TG) level, serum high-density lipoprotein (HDL) level, blood pressure (BP) and waist circumference (WC), as per the National Cholesterol Education Program (NCEP) Adult Treatment Panel III (ATP III) criteria. Data analysis includes mean and standard deviation (SD) for numerical variables with an unpaired t-test to compare means and percentage and proportions for categorical variables with the Chi-square test for the associations. Multivariate logistic regression was used for assessing the predictors of MetS The prevalence of components of MetS, that is obesity, hypertension (HTN), TG and HDL components, was 64.0% (192), 45.7% (137), 46.0% (138) and 30% (90), respectively. Overall, MetS was 57% (170). Moderate activity of 150 min/week, sitting/reclining, WC, diastolic BP, TG and HDL had a significant association with MetS MetS was highly associated with newly diagnosed T2DM with obesity being the most common component.

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来源期刊

Accounts of Chemical Research 化学-化学综合

CiteScore

31.40

自引率

1.10%

发文量

312

审稿时长

2 months

期刊介绍： Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.