细菌代谢组学：人类福祉的当前应用和未来方面。

IF 1.3 3区医学 Q3 CHEMISTRY, APPLIED

Journal of Asian Natural Products Research Pub Date : 2024-07-30 DOI:10.1080/10286020.2024.2385365

Qazi Mohammad Sajid Jamal, Varish Ahmad

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引用次数: 0

摘要

失衡的微生物群与多种疾病有关，如癌症、炎症性肠病、肥胖甚至神经系统疾病。细菌及其副产品被用于各种工业和临床用途。根据代谢组研究确定的代谢物对宿主和肠道微生物群相互作用的生物学影响，选择了正在讨论的代谢物。利用统计学和机器学习分析分离细菌代谢物，为细菌及其代谢物在环境和医学科学中的应用创造了新的机会。因此，本综述将讨论代谢物的生产策略、方法以及细菌代谢物对人类福祉的重要性。

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Bacterial metabolomics: current applications for human welfare and future aspects.

An imbalanced microbiome is linked to several diseases, such as cancer, inflammatory bowel disease, obesity, and even neurological disorders. Bacteria and their by-products are used for various industrial and clinical purposes. The metabolites under discussion were chosen based on their biological impacts on host and gut microbiota interactions as established by metabolome research. The separation of bacterial metabolites by using statistics and machine learning analysis creates new opportunities for applications of bacteria and their metabolites in the environmental and medical sciences. Thus, the metabolite production strategies, methodologies, and importance of bacterial metabolites for human well-being are discussed in this review.

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来源期刊

Journal of Asian Natural Products Research 医学-药学

CiteScore

3.20

自引率

5.90%

发文量

审稿时长

2.3 months

期刊介绍： The Journal of Asian Natural Products Research (JANPR) publishes chemical and pharmaceutical studies in the English language in the field of natural product research on Asian ethnic medicine. The journal publishes work from scientists in Asian countries, e.g. China, Japan, Korea and India, including contributions from other countries concerning natural products of Asia. The journal is chemistry-orientated. Major fields covered are: isolation and structural elucidation of natural constituents (including those for non-medical uses), synthesis and transformation (including biosynthesis and biotransformation) of natural products, pharmacognosy, and allied topics. Biological evaluation of crude extracts are acceptable only as supporting data for pure isolates with well-characterized structures. All published research articles in this journal have undergone rigorous peer review, based on initial editor screening and anonymized refereeing by at least two expert referees.