Ishita Mostafa, Umme Habiba Lamiya, Md Golam Rasul, Nurun Nahar Naila, Shah Mohammad Fahim, S M Tafsir Hasan, Michael J Barratt, Jeffrey I Gordon, Tahmeed Ahmed
{"title":"开发可在货架上保存的微生物群定向补充食品配方及其可接受性。","authors":"Ishita Mostafa, Umme Habiba Lamiya, Md Golam Rasul, Nurun Nahar Naila, Shah Mohammad Fahim, S M Tafsir Hasan, Michael J Barratt, Jeffrey I Gordon, Tahmeed Ahmed","doi":"10.1177/03795721241250104","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>A randomized controlled trial in Bangladeshi children aged 12 to 18 months with moderate acute malnutrition found that dietary supplementation with the microbiota-directed complementary food (MDCF-2) significantly improved weight gain and repaired gut microbiota compared to the ready-to-use supplementary food. However, the MDCF-2 formulation was made daily from locally available ingredients and the need for a packaged, nutritionally compliant, and organoleptically acceptable MDCF-2 prototype was essential for future large-scale clinical studies.</p><p><strong>Objective: </strong>The study aimed to develop and assess the acceptability of 3 alternative foil-packaged formulations of MDCF-2 in comparison to current MDCF-2.</p><p><strong>Methods: </strong>Of the 3 packaged formulations, the Jumpstart version was provided in 2 sachets, the other 2 formulations were provided in a retort-stable foil pouch extended by sterilization, and microbiological growth was monitored over 10 months. The acceptability study included 40 children aged 8 to 12 months living in an urban slum in Dhaka, and the organoleptic properties were assessed using a 7-point hedonic scale.</p><p><strong>Results: </strong>In the 100 g distributed over the 2 sessions, children consumed 82.5 ± 7.84 g (mean ± SD) of kitchen-prepared MDCF-2, 85.4 ± 7.15 g of the \"Jumpstart\" MDCF-2 formulation, 85.4 ± 8.70 g of the MDCF-2 with green banana powder, and 86.2 ± 4.26 g of the MDCF-2 with sweet potato formulation. The \"Jumpstart\" MDCF-2 and MDCF-2 with sweet potato achieved the highest overall acceptability scores on the hedonic scale; although none of the shelf-stable formulations were significantly different from the kitchen-prepared MDCF-2.</p><p><strong>Conclusions: </strong>Packaged, shelf-stable prototypes of MDCF-2 exhibited comparable acceptability among Bangladeshi children aged 8 to 12 months to the original freshly prepared formulation.</p><p><strong>Plain language title: </strong>Development and Acceptability of Shelf-Stable Microbiota-Directed Complementary Foods.</p>","PeriodicalId":12394,"journal":{"name":"Food and Nutrition Bulletin","volume":" ","pages":"67-73"},"PeriodicalIF":1.8000,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Development and Acceptability of Shelf-Stable Microbiota Directed Complementary Food Formulations.\",\"authors\":\"Ishita Mostafa, Umme Habiba Lamiya, Md Golam Rasul, Nurun Nahar Naila, Shah Mohammad Fahim, S M Tafsir Hasan, Michael J Barratt, Jeffrey I Gordon, Tahmeed Ahmed\",\"doi\":\"10.1177/03795721241250104\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>A randomized controlled trial in Bangladeshi children aged 12 to 18 months with moderate acute malnutrition found that dietary supplementation with the microbiota-directed complementary food (MDCF-2) significantly improved weight gain and repaired gut microbiota compared to the ready-to-use supplementary food. However, the MDCF-2 formulation was made daily from locally available ingredients and the need for a packaged, nutritionally compliant, and organoleptically acceptable MDCF-2 prototype was essential for future large-scale clinical studies.</p><p><strong>Objective: </strong>The study aimed to develop and assess the acceptability of 3 alternative foil-packaged formulations of MDCF-2 in comparison to current MDCF-2.</p><p><strong>Methods: </strong>Of the 3 packaged formulations, the Jumpstart version was provided in 2 sachets, the other 2 formulations were provided in a retort-stable foil pouch extended by sterilization, and microbiological growth was monitored over 10 months. The acceptability study included 40 children aged 8 to 12 months living in an urban slum in Dhaka, and the organoleptic properties were assessed using a 7-point hedonic scale.</p><p><strong>Results: </strong>In the 100 g distributed over the 2 sessions, children consumed 82.5 ± 7.84 g (mean ± SD) of kitchen-prepared MDCF-2, 85.4 ± 7.15 g of the \\\"Jumpstart\\\" MDCF-2 formulation, 85.4 ± 8.70 g of the MDCF-2 with green banana powder, and 86.2 ± 4.26 g of the MDCF-2 with sweet potato formulation. 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Development and Acceptability of Shelf-Stable Microbiota Directed Complementary Food Formulations.
Background: A randomized controlled trial in Bangladeshi children aged 12 to 18 months with moderate acute malnutrition found that dietary supplementation with the microbiota-directed complementary food (MDCF-2) significantly improved weight gain and repaired gut microbiota compared to the ready-to-use supplementary food. However, the MDCF-2 formulation was made daily from locally available ingredients and the need for a packaged, nutritionally compliant, and organoleptically acceptable MDCF-2 prototype was essential for future large-scale clinical studies.
Objective: The study aimed to develop and assess the acceptability of 3 alternative foil-packaged formulations of MDCF-2 in comparison to current MDCF-2.
Methods: Of the 3 packaged formulations, the Jumpstart version was provided in 2 sachets, the other 2 formulations were provided in a retort-stable foil pouch extended by sterilization, and microbiological growth was monitored over 10 months. The acceptability study included 40 children aged 8 to 12 months living in an urban slum in Dhaka, and the organoleptic properties were assessed using a 7-point hedonic scale.
Results: In the 100 g distributed over the 2 sessions, children consumed 82.5 ± 7.84 g (mean ± SD) of kitchen-prepared MDCF-2, 85.4 ± 7.15 g of the "Jumpstart" MDCF-2 formulation, 85.4 ± 8.70 g of the MDCF-2 with green banana powder, and 86.2 ± 4.26 g of the MDCF-2 with sweet potato formulation. The "Jumpstart" MDCF-2 and MDCF-2 with sweet potato achieved the highest overall acceptability scores on the hedonic scale; although none of the shelf-stable formulations were significantly different from the kitchen-prepared MDCF-2.
Conclusions: Packaged, shelf-stable prototypes of MDCF-2 exhibited comparable acceptability among Bangladeshi children aged 8 to 12 months to the original freshly prepared formulation.
Plain language title: Development and Acceptability of Shelf-Stable Microbiota-Directed Complementary Foods.
期刊介绍：
The Food and Nutrition Bulletin (FNB,) is a peer-reviewed, academic journal published quarterly by the Nevin Scrimshaw International Nutrition Foundation. The Journal is one of the leading resources used by researchers, academics, nutrition policy makers and planners in over 125 countries to obtain the most current research and policy information related to nutrition in developing countries.
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