通过超声波检查确定的迷走神经大小与有血管风险因素患者的白质病变有关。

IF 1.3 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING
Journal of Ultrasound Pub Date : 2024-09-01 Epub Date: 2024-07-29 DOI:10.1007/s40477-024-00936-2
Tomohisa Nezu, Futoshi Eto, Akemi Hironaka, Shiro Aoki, Shuichiro Neshige, Saki Tasaka, Hikari Kirimoto, Hirofumi Maruyama
{"title":"通过超声波检查确定的迷走神经大小与有血管风险因素患者的白质病变有关。","authors":"Tomohisa Nezu, Futoshi Eto, Akemi Hironaka, Shiro Aoki, Shuichiro Neshige, Saki Tasaka, Hikari Kirimoto, Hirofumi Maruyama","doi":"10.1007/s40477-024-00936-2","DOIUrl":null,"url":null,"abstract":"<p><strong>Purpose: </strong>The cross-sectional area (CSA) of the cervical vagus nerve (VN), as assessed through ultrasonography, might be linked to autonomic nervous system dysfunction. Hypertension is the primary factor associated with cerebral white matter lesions (WMLs), but there is also evidence of a connection with autonomic nervous system dysfunction. However, the associations between WMLs and VN size are unclear. Our objective was to investigate the associations between WMLs and VN size in patients with vascular risk factors.</p><p><strong>Methods: </strong>The CSA of the VN was evaluated using carotid ultrasonography in patients with a history of stroke (acute or chronic) and comorbidities (n = 196, 70.2 ± 12.7 years). Common carotid artery (CCA) intima-media thickness and interadventitial diameter (IAD) were also measured. The severity of the WMLs was assessed by the Fazekas classification and Scheltens' scale.</p><p><strong>Results: </strong>The CSA of the right VN (2.08 ± 0.65 mm<sup>2</sup>) was significantly greater than that of the CSA of the left VN (1.56 ± 0.44 mm<sup>2</sup>) (P < 0.001). Multiple linear regression analyses revealed that older age, hypertension, increased right CCA IAD, and decreased CSA of the right VN (standardized partial regression coefficient [β] - 0.226; P < 0.001) were independently associated with the severity of WMLs (Scheltens' scale). A decreased CSA of the left VN was also associated with the severity of WMLs (β = - 0.239; P < 0.001).</p><p><strong>Conclusion: </strong>VN size determined via ultrasonography was associated with the severity of WMLs. While these findings do not establish a causal relationship, they suggest that autonomic nervous system dysfunction is involved in the progression of WMLs.</p>","PeriodicalId":51528,"journal":{"name":"Journal of Ultrasound","volume":null,"pages":null},"PeriodicalIF":1.3000,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11333691/pdf/","citationCount":"0","resultStr":"{\"title\":\"Vagus nerve size determined via ultrasonography is associated with white matter lesions in patients with vascular risk factors.\",\"authors\":\"Tomohisa Nezu, Futoshi Eto, Akemi Hironaka, Shiro Aoki, Shuichiro Neshige, Saki Tasaka, Hikari Kirimoto, Hirofumi Maruyama\",\"doi\":\"10.1007/s40477-024-00936-2\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Purpose: </strong>The cross-sectional area (CSA) of the cervical vagus nerve (VN), as assessed through ultrasonography, might be linked to autonomic nervous system dysfunction. Hypertension is the primary factor associated with cerebral white matter lesions (WMLs), but there is also evidence of a connection with autonomic nervous system dysfunction. However, the associations between WMLs and VN size are unclear. Our objective was to investigate the associations between WMLs and VN size in patients with vascular risk factors.</p><p><strong>Methods: </strong>The CSA of the VN was evaluated using carotid ultrasonography in patients with a history of stroke (acute or chronic) and comorbidities (n = 196, 70.2 ± 12.7 years). Common carotid artery (CCA) intima-media thickness and interadventitial diameter (IAD) were also measured. The severity of the WMLs was assessed by the Fazekas classification and Scheltens' scale.</p><p><strong>Results: </strong>The CSA of the right VN (2.08 ± 0.65 mm<sup>2</sup>) was significantly greater than that of the CSA of the left VN (1.56 ± 0.44 mm<sup>2</sup>) (P < 0.001). Multiple linear regression analyses revealed that older age, hypertension, increased right CCA IAD, and decreased CSA of the right VN (standardized partial regression coefficient [β] - 0.226; P < 0.001) were independently associated with the severity of WMLs (Scheltens' scale). A decreased CSA of the left VN was also associated with the severity of WMLs (β = - 0.239; P < 0.001).</p><p><strong>Conclusion: </strong>VN size determined via ultrasonography was associated with the severity of WMLs. While these findings do not establish a causal relationship, they suggest that autonomic nervous system dysfunction is involved in the progression of WMLs.</p>\",\"PeriodicalId\":51528,\"journal\":{\"name\":\"Journal of Ultrasound\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":1.3000,\"publicationDate\":\"2024-09-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11333691/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Ultrasound\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1007/s40477-024-00936-2\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2024/7/29 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"Q3\",\"JCRName\":\"RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Ultrasound","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1007/s40477-024-00936-2","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/7/29 0:00:00","PubModel":"Epub","JCR":"Q3","JCRName":"RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING","Score":null,"Total":0}
引用次数: 0

摘要

目的:通过超声波检查评估的颈迷走神经(VN)横截面积(CSA)可能与自主神经系统功能障碍有关。高血压是与脑白质病变(WMLs)相关的主要因素,但也有证据表明与自主神经系统功能障碍有关。然而,WMLs 与 VN 大小之间的关系尚不清楚。我们的目的是研究有血管风险因素的患者的 WMLs 与 VN 大小之间的关系:方法:对有中风(急性或慢性)病史和合并症的患者(n = 196,70.2 ± 12.7 岁)使用颈动脉超声波对 VN 的 CSA 进行评估。此外,还测量了颈总动脉 (CCA) 的内膜厚度和动脉间直径 (IAD)。WMLs的严重程度由Fazekas分类法和Scheltens量表进行评估:结果:右侧 VN 的 CSA(2.08 ± 0.65 mm2)明显大于左侧 VN 的 CSA(1.56 ± 0.44 mm2):通过超声波检查确定的 VN 大小与 WML 的严重程度有关。虽然这些发现并不能确定因果关系,但它们表明自律神经系统功能障碍与 WMLs 的进展有关。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Vagus nerve size determined via ultrasonography is associated with white matter lesions in patients with vascular risk factors.

Purpose: The cross-sectional area (CSA) of the cervical vagus nerve (VN), as assessed through ultrasonography, might be linked to autonomic nervous system dysfunction. Hypertension is the primary factor associated with cerebral white matter lesions (WMLs), but there is also evidence of a connection with autonomic nervous system dysfunction. However, the associations between WMLs and VN size are unclear. Our objective was to investigate the associations between WMLs and VN size in patients with vascular risk factors.

Methods: The CSA of the VN was evaluated using carotid ultrasonography in patients with a history of stroke (acute or chronic) and comorbidities (n = 196, 70.2 ± 12.7 years). Common carotid artery (CCA) intima-media thickness and interadventitial diameter (IAD) were also measured. The severity of the WMLs was assessed by the Fazekas classification and Scheltens' scale.

Results: The CSA of the right VN (2.08 ± 0.65 mm2) was significantly greater than that of the CSA of the left VN (1.56 ± 0.44 mm2) (P < 0.001). Multiple linear regression analyses revealed that older age, hypertension, increased right CCA IAD, and decreased CSA of the right VN (standardized partial regression coefficient [β] - 0.226; P < 0.001) were independently associated with the severity of WMLs (Scheltens' scale). A decreased CSA of the left VN was also associated with the severity of WMLs (β = - 0.239; P < 0.001).

Conclusion: VN size determined via ultrasonography was associated with the severity of WMLs. While these findings do not establish a causal relationship, they suggest that autonomic nervous system dysfunction is involved in the progression of WMLs.

求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
Journal of Ultrasound
Journal of Ultrasound RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING-
CiteScore
4.10
自引率
15.00%
发文量
133
期刊介绍: The Journal of Ultrasound is the official journal of the Italian Society for Ultrasound in Medicine and Biology (SIUMB). The journal publishes original contributions (research and review articles, case reports, technical reports and letters to the editor) on significant advances in clinical diagnostic, interventional and therapeutic applications, clinical techniques, the physics, engineering and technology of ultrasound in medicine and biology, and in cross-sectional diagnostic imaging. The official language of Journal of Ultrasound is English.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信