基于计算机断层扫描的对比特征,用于区分胃肠道外间质瘤和腹腔内纤维瘤病。

IF 1.4 4区 医学 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING
Lijing Zhang, Yongbo Li, Xinxin Luo, Deqi Li, Linlin Yin, Jiayue Li, Li Zhang
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引用次数: 0

摘要

目的:本研究旨在确定区分胃肠道外间质瘤(eGISTs)和腹腔内纤维瘤病(IAF)的计算机断层扫描(CT)标准:对31例病理确诊病例的CT图像进行回顾性分析,其中包括17例eGISTs和14例IAF。对各种参数[如病变位置、轮廓特征、边界划分、增强模式、是否存在区域内坏死、血管、空气、脂肪和出血、长径(LD)、LD/短径(SD)比值和体积(LD × SD × 高径)]进行了细致评估。此外,还量化了动脉期和门静脉期的增强程度以及两期病变与主动脉的 CT 衰减比。统计分析采用费雪精确检验、学生 t 检验和接收者操作特征曲线来确定重要的 CT 标准。对单一和组合 CT 标准进行了敏感性和特异性评估:eGISTs和IAF的重要鉴别标准包括:非肠系膜定位、轮廓不规则、边界清晰、异质强化、有组织内坏死和血管、无组织内脂肪、LD超过9.6厘米、LD/SD比值>1.22、体积超过603.3立方厘米(P<0.05)。综合上述标准中的七项或更多标准,特异性达到 100%:结论:已确定了十项不同的 CT 标准来区分 eGIST 和 IAF,主要包括非肠系膜定位、轮廓不规则、边界清晰、异质强化、存在区域内坏死和血管、无区域内脂肪、LD >9.6 cm、LD/SD 比值 >1.22 和体积超过 603.3 cm3:目前的研究结果确立了在临床环境中区分 eGIST 和 IAF 的 CT 标准。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Computed tomography-based contrast features for distinguishing extra-gastrointestinal stromal tumors from intra-abdominal fibromatosis.

Purpose: This study aims to define the computed tomography (CT) criteria that distinguish extra-gastrointestinal stromal tumors (eGISTs) from intra-abdominal fibromatosis (IAF).

Methods: Retrospective analysis was conducted on CT images obtained from 31 pathologically confirmed cases, including 17 cases of eGISTs and 14 of IAF. Various parameters [e.g., lesion location, contour characteristics, border delineation, enhancement patterns, presence of intralesional necrosis, vessels, air, fat, and hemorrhage, the long diameter (LD), LD/short diameter (SD) ratio, and volume (LD × SD × height diameter)] were meticulously evaluated. In addition, the degree of enhancement during arterial and portal venous phases and the lesion-to-aorta CT attenuation ratio during both phases were quantified. Statistical analysis was performed using Fisher's exact test, the Student's t-test, and the receiver operating characteristic curve to identify significant CT criteria. Sensitivity and specificity assessments were conducted for single and combined CT criteria.

Results: Significant differentiators between eGISTs and IAF include non-mesenteric localization, irregular contour, well-defined borders, heterogeneous enhancement, presence of intralesional necrosis and vessels, and absence of intralesional fat, with LD exceeding 9.6 cm, an LD/SD ratio >1.22, and volume surpassing 603.3 cm3 (P < 0.05). A combination of seven or more of these criteria yielded a specificity of 100%.

Conclusion: Ten distinct CT criteria have been identified to distinguish eGISTs from IAF, notably encompassing non-mesenteric localization, irregular contour, well-defined borders, heterogeneous enhancement, presence of intralesional necrosis and vessels, absence of intralesional fat, LD >9.6 cm, an LD/SD ratio >1.22, and volume surpassing 603.3 cm3.

Clinical significance: The current findings establish CT criteria to distinguish eGISTs from IAF in a clinical setting.

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来源期刊
Diagnostic and interventional radiology
Diagnostic and interventional radiology Medicine-Radiology, Nuclear Medicine and Imaging
自引率
4.80%
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0
期刊介绍: Diagnostic and Interventional Radiology (Diagn Interv Radiol) is the open access, online-only official publication of Turkish Society of Radiology. It is published bimonthly and the journal’s publication language is English. The journal is a medium for original articles, reviews, pictorial essays, technical notes related to all fields of diagnostic and interventional radiology.
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