与先天性免疫错误有关的小儿淋巴细胞增生性疾病。

IF 4.5 3区医学 Q2 IMMUNOLOGY

Clinical immunology Pub Date : 2024-07-26 DOI:10.1016/j.clim.2024.110332

Jinjun Cheng , Blachy J. Dávila Saldaña , Shanmuganathan Chandrakasan , Michael Keller

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引用次数: 0

摘要

非恶性和恶性淋巴增生性疾病（LPD）常见于先天性免疫错误（IEI）患者，可能是先兆表现，也可能在 IEI 病程中发展。在此，我们回顾了与 IEI 相关的良性和恶性 LPD 的临床、组织病理学和分子特征，并探讨了诊断方面的难题。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Pediatric lymphoproliferative disorders associated with inborn errors of immunity

Both non-malignant and malignant lymphoproliferative disorders (LPD) are commonly seen in patients with inborn errors of immunity (IEI), which may be the presenting manifestations or may develop during the IEI disease course. Here we review the clinical, histopathological, and molecular features of benign and malignant LPD associated with IEI and recognize the diagnostic challenges.

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来源期刊

Clinical immunology 医学-免疫学

CiteScore

12.30

自引率

1.20%

发文量

212

审稿时长

34 days

期刊介绍： Clinical Immunology publishes original research delving into the molecular and cellular foundations of immunological diseases. Additionally, the journal includes reviews covering timely subjects in basic immunology, along with case reports and letters to the editor.