Federico Castelletti, Guido Consonni, Marco L Della Vedova
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引用次数: 0
摘要
本文的研究范围是涉及分类变量的多变量环境。在对一个变量进行外部操作后,目标是评估其对相关结果的因果影响。一个典型的情景是由代表生活方式、身心特征、症状和风险因素的变量组成的系统,其结果是是否患有某种疾病。这些变量以复杂的方式相互关联,使得干预效果可以通过多种途径传播。我们方法的一个显著特点是在估算因果效应的同时,考虑到依赖结构(我们通过有向无环图(DAG)表示)和 DAG 模型参数的不确定性。具体来说,我们提出了一种马尔可夫链蒙特卡洛算法,该算法基于高效的可逆跳跃建议方案,以 DAG 和参数的联合后验为目标。我们通过大量的模拟研究验证了我们的方法,并证明它在估计精度方面优于目前最先进的程序。最后,我们将我们的方法应用于分析本科生抑郁和焦虑的数据集。
Joint structure learning and causal effect estimation for categorical graphical models.
The scope of this paper is a multivariate setting involving categorical variables. Following an external manipulation of one variable, the goal is to evaluate the causal effect on an outcome of interest. A typical scenario involves a system of variables representing lifestyle, physical and mental features, symptoms, and risk factors, with the outcome being the presence or absence of a disease. These variables are interconnected in complex ways, allowing the effect of an intervention to propagate through multiple paths. A distinctive feature of our approach is the estimation of causal effects while accounting for uncertainty in both the dependence structure, which we represent through a directed acyclic graph (DAG), and the DAG-model parameters. Specifically, we propose a Markov chain Monte Carlo algorithm that targets the joint posterior over DAGs and parameters, based on an efficient reversible-jump proposal scheme. We validate our method through extensive simulation studies and demonstrate that it outperforms current state-of-the-art procedures in terms of estimation accuracy. Finally, we apply our methodology to analyze a dataset on depression and anxiety in undergraduate students.
期刊介绍:
The International Biometric Society is an international society promoting the development and application of statistical and mathematical theory and methods in the biosciences, including agriculture, biomedical science and public health, ecology, environmental sciences, forestry, and allied disciplines. The Society welcomes as members statisticians, mathematicians, biological scientists, and others devoted to interdisciplinary efforts in advancing the collection and interpretation of information in the biosciences. The Society sponsors the biennial International Biometric Conference, held in sites throughout the world; through its National Groups and Regions, it also Society sponsors regional and local meetings.