Ali Saridas, Nafis Vural, Murat Duyan, Hasan Can Guven, Elif Ertas, Basar Cander
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引用次数: 0
摘要
导言 急性阑尾炎(AA)是导致各年龄段人群急性腹痛的主要疾病。本研究旨在确定在急诊科(ED)就诊的急性阑尾炎患者中,血红蛋白、白蛋白、淋巴细胞和血小板(HALP)和改良 HALP(m-HALP)评分在复杂性阑尾炎和非复杂性阑尾炎之间是否存在差异。此外,本研究还旨在探讨 HALP 和 m-HALP 评分是否优于其他生物标志物。材料和方法 该回顾性分析包括年龄在 18 岁或以上、被诊断为 AA 并在一家三甲医院急诊科就诊的成年患者。患者分为两组:复杂性阑尾炎(CA)和非复杂性阑尾炎(UCA)。采用接收者操作特征分析法确定诊断值测量的临界值。结果 共纳入 436 例患者(CA:126 例,UCA:310 例)。结果发现,中性粒细胞与淋巴细胞比值(NLR)、中性粒细胞与白蛋白比值、全身免疫炎症指数(SII)、全身炎症反应指数(SIRI)和泛免疫炎症值(PIV)在检测 CA 方面具有可接受的诊断能力(曲线下面积 [AUC]:0.735-0.783)。在检测 UCA 时,HALP 和 m-HALP 的诊断能力尚可(AUC 分别为 0.64 和 0.68)。结论 本研究发现,虽然 PIV、SIRI、SII 和 NLR 在区分 CA 和 UCA 方面具有可接受的诊断价值,但 HALP 和 m-HALP 的诊断价值一般。
Comparison of the ability of newly inflammatory markers to predict complicated appendicitis
Introduction Acute appendicitis (AA) is the predominant condition responsible for acute abdominal pain across all age demographics. The purpose of this research is to determine if the hemoglobin, albumin, lymphocyte, and platelet (HALP) and modified HALP (m-HALP) scores differ between complicated and uncomplicated appendicitis in patients diagnosed with AA who have applied to the emergency department (ED). Additionally, this study aims to investigate whether HALP and m-HALP scores are superior to other biomarkers. Materials and methods The retrospective analysis included adult patients, aged eighteen or older, who were diagnosed with AA, and sought treatment at the ED of a tertiary hospital. Patients were divided into two groups: complicated appendicitis (CA) and uncomplicated appendicitis (UCA). The cut-off in diagnostic value measurements was determined using the receiver operating characteristic analysis. Results A total of 436 patients (CA: 126, UCA: 310) were included. Neutrophil-to-lymphocyte ratio (NLR), neutrophil-to-albumin ratio, systemic immune-inflammation index (SII), systemic inflammation response index (SIRI), and pan-immune inflammation value (PIV) were found to have acceptable diagnostic power in CA detection (area under the curve [AUC]: 0.735–0.783). In detecting UCA, HALP and m-HALP were of fair diagnostic power (AUC: 0.64, 0.68, respectively). Conclusions In this study, we found that although PIV, SIRI, SII, and NLR had acceptable diagnostic values in distinguishing CA and UCA, HALP and m-HALP had fair diagnostic values.
期刊介绍:
Open Medicine is an open access journal that provides users with free, instant, and continued access to all content worldwide. The primary goal of the journal has always been a focus on maintaining the high quality of its published content. Its mission is to facilitate the exchange of ideas between medical science researchers from different countries. Papers connected to all fields of medicine and public health are welcomed. Open Medicine accepts submissions of research articles, reviews, case reports, letters to editor and book reviews.