布里渊特征与肖尔特波之间的互补性，用于控制培养细胞的纤维胶原介质的弹性

IF 5.3 2区材料科学 Q2 MATERIALS SCIENCE, MULTIDISCIPLINARY

APL Materials Pub Date : 2024-07-25 DOI:10.1063/5.0225336

A. Hamraoui, O. Sénépart, L. Belliard

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引用次数: 0

摘要

利用纤维胶原调节细胞外基质（ECM）的弹性，通过复制体内机械信号，为再生医学、药物发现和疾病建模提供了巨大的潜力。这能加深对细胞反应的了解，促进治疗创新。然而，目前仍缺乏对 ECM 弹性的精确测量。本研究将时间分辨布里渊光谱学和脉冲激光诱导肖尔特波生成结合起来。我们测量了胶原蛋白纤维化如何影响声速和折射率。这些见解将推动组织工程学和细胞生物力学的发展。

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Complementarity between Brillouin signature and Scholte wave for controlled elasticity in fibrillated collagen medium for culture cell

Modulating extracellular matrix (ECM) elasticity with fibrillar collagen offers great potential for regenerative medicine, drug discovery, and disease modeling by replicating in vivo mechanical signals. This enhances the understanding of cellular responses and fosters therapeutic innovation. However, precise ECM elasticity measurements are still lacking. This study couples time-resolved Brillouin spectroscopy and pulsed laser-induced Scholte wave generation. We measure how collagen fibrillation affects sound velocity and refractive index. These insights are advancing tissue engineering and cellular biomechanics.

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来源期刊

APL Materials NANOSCIENCE & NANOTECHNOLOGYMATERIALS SCIE-MATERIALS SCIENCE, MULTIDISCIPLINARY

CiteScore

9.60

自引率

3.30%

发文量

199

审稿时长

2 months

期刊介绍： APL Materials features original, experimental research on significant topical issues within the field of materials science. In order to highlight research at the forefront of materials science, emphasis is given to the quality and timeliness of the work. The journal considers theory or calculation when the work is particularly timely and relevant to applications. In addition to regular articles, the journal also publishes Special Topics, which report on cutting-edge areas in materials science, such as Perovskite Solar Cells, 2D Materials, and Beyond Lithium Ion Batteries.