与大麻主观效应相关的环境因素：系统回顾和荟萃分析。

IF 7.5 1区医学 Q1 BEHAVIORAL SCIENCES

Neuroscience and Biobehavioral Reviews Pub Date : 2024-07-25 DOI:10.1016/j.neubiorev.2024.105822

Mouktika M. Ayyagari , Derek Heim , Harry R. Sumnall , Rebecca L. Monk

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引用次数: 0

摘要

背景：大麻是在各种社会和环境背景下消费的，这些背景可能是主观效果的重要预测因素。本系统综述和荟萃分析旨在研究环境因素与大麻主观效应之间的关系：在 PRISMA 的指导下，对 MEDLINE、Embase、PsycINFO、Global Health 和 Google Scholar 进行了检索，共获得 29 项研究结果：研究类型（生态学瞬间评估或实验）对中毒效应有显著的预测作用，与生态学瞬间评估（EMA）研究（z =.071，95% CI [.011，.130]，p =.02）相比，实验研究的集合效应大小更大（z =.296，95% CI [.132，.478]，p =.004）。环境条件（环境、社会群体、预期、一天中的时间、一周中的哪一天）对大麻的影响没有显著的预测作用：结论：研究结果表明，情境条件与主观效果之间没有明显联系。然而，由于目前的文献在方法论上还很薄弱，因此得出主观效果不受环境因素影响的结论可能为时尚早。考虑到政策和治疗方面的影响，建议进行复制和改进研究。

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Contextual factors associated with subjective effects of cannabis: A systematic review and meta-analysis

Background

Cannabis is consumed in various social and environmental settings, and such contexts may be important predictors of subjective effects. The aim of this systematic review and meta-analysis was to examine the relationship between contextual factors and subjective effects of cannabis.

Methods

A PRISMA-guided search of MEDLINE, Embase, PsycINFO, Global Health, and Google Scholar yielded 29 studies.

Results

Study type (Ecological Momentary Assessment or Experimental) was a significant predictor of intoxication effects, and experimental studies had a greater pooled effect size (z =.296,95 % CI [.132,.478], p=.004) than Ecological Momentary Assessment (EMA) studies (z =.071,95 % CI [.011,.130], p =.02). Contextual conditions (environment, social group, expectancy, time of day, day of week) were not significant predictors of cannabis effects.

Conclusion

Findings did not point to a significant association between contextual conditions and subjective effects. However, as current literature is methodologically weak, it may be premature to conclude that subjective effects are not shaped by contextual factors. In view of policy and therapeutic implications, replications and study refinements are recommended.

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来源期刊

Neuroscience and Biobehavioral Reviews 医学-行为科学

CiteScore

14.20

自引率

3.70%

发文量

466

审稿时长

6 months

期刊介绍： The official journal of the International Behavioral Neuroscience Society publishes original and significant review articles that explore the intersection between neuroscience and the study of psychological processes and behavior. The journal also welcomes articles that primarily focus on psychological processes and behavior, as long as they have relevance to one or more areas of neuroscience.