UNC93B1 变体通过 TLR 激活促进系统性红斑狼疮的发生。

IF 29.4 1区医学 Q1 RHEUMATOLOGY

Nature Reviews Rheumatology Pub Date : 2024-07-26 DOI:10.1038/s41584-024-01147-z

Holly Webster

引用次数: 0

摘要

两项研究发现，UNC93B1 的变体与 TLR7 和 TLR8 活性增强以及系统性红斑狼疮的发生有关。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

UNC93B1 variants promote SLE via TLR activation

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UNC93B1 variants promote SLE via TLR activation

Two studies have identified variants of UNC93B1 that are associated with enhanced TLR7 and TLR8 activity and the development of systemic lupus erythematosus.

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来源期刊

Nature Reviews Rheumatology 医学-风湿病学

CiteScore

29.90

自引率

0.90%

发文量

137

审稿时长

6-12 weeks

期刊介绍： Nature Reviews Rheumatology is part of the Nature Reviews portfolio of journals. The journal scope covers the entire spectrum of rheumatology research. We ensure that our articles are accessible to the widest possible audience.