设计和合成一种新型双核钯络合物，作为神经递质多巴胺的开启荧光受体。

IF 2.6 4区化学 Q2 BIOCHEMICAL RESEARCH METHODS

Journal of Fluorescence Pub Date : 2024-07-26 DOI:10.1007/s10895-024-03861-z

Arunangshu Kundu, Gobinda Chandra De, Sushobhan Ghosh

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引用次数: 0

摘要

通过硝酸四甲基乙二胺钯和焦麦饭石酸钠盐的反应，合成了一种新型双核钯络合物。紫外可见光、核磁共振和荧光滴定技术表明，这种双核钯复合物能与神经递质多巴胺相互作用。随着神经递质多巴胺的逐渐加入，水溶液中钯复合物的荧光增强，从而使该复合物成为神经递质多巴胺的荧光传感器。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Design and Synthesis of a Novel Binuclear Palladium Complex as a Turn on Fluorescent Receptor for Neurotransmitter Dopamine.

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Design and Synthesis of a Novel Binuclear Palladium Complex as a Turn on Fluorescent Receptor for Neurotransmitter Dopamine.

A novel binuclear palladium complex has been synthesized by the reaction of tetramethylethylenediamine palladium nitrate and sodium salt of pyromellitic acid. UV vis, NMR as well as fluorescent titration techniques show that this binuclear palladium complex interacts with neurotransmitter dopamine. The fluorescence of the palladium complex in aqueous solution gets enhanced with the gradual addition of the neurotransmitter dopamine which makes this complex to act as a turn on fluorescent sensor for neurotransmitter dopamine.

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来源期刊

Journal of Fluorescence 化学-分析化学

CiteScore

4.60

自引率

7.40%

发文量

203

审稿时长

5.4 months

期刊介绍： Journal of Fluorescence is an international forum for the publication of peer-reviewed original articles that advance the practice of this established spectroscopic technique. Topics covered include advances in theory/and or data analysis, studies of the photophysics of aromatic molecules, solvent, and environmental effects, development of stationary or time-resolved measurements, advances in fluorescence microscopy, imaging, photobleaching/recovery measurements, and/or phosphorescence for studies of cell biology, chemical biology and the advanced uses of fluorescence in flow cytometry/analysis, immunology, high throughput screening/drug discovery, DNA sequencing/arrays, genomics and proteomics. Typical applications might include studies of macromolecular dynamics and conformation, intracellular chemistry, and gene expression. The journal also publishes papers that describe the synthesis and characterization of new fluorophores, particularly those displaying unique sensitivities and/or optical properties. In addition to original articles, the Journal also publishes reviews, rapid communications, short communications, letters to the editor, topical news articles, and technical and design notes.