{"title":"空气污染物暴露与精液质量的个体和联合关联：中国温州的一项回顾性纵向研究。","authors":"Xuchao Dai, Guangyuan Liu, Chengshuang Pan, Feidi Li, Yawen Liu, Jiaxin Liu, Gang Chen, Mengqi Zhang, Qianjin Fei, Jiujia Zheng, Hong Huang, Zhigang Wu","doi":"10.1007/s00420-024-02095-7","DOIUrl":null,"url":null,"abstract":"<p><strong>Purpose: </strong>The impact of air pollution on semen quality has been confirmed, yet the joint effect remains unclear. We evaluate the individual and joint associations of particulate (PM<sub>2.5</sub> and PM<sub>10</sub>) and gaseous pollutants (NO<sub>2</sub>, SO<sub>2</sub>, O<sub>3</sub> and CO) with semen quality.</p><p><strong>Methods: </strong>We included 5,114 men in this study from 2014 to 2022. The individual and joint associations were measured by multiple linear regression models.</p><p><strong>Results: </strong>Sperm motility and semen volume were inversely associated with pollutant concentrations during every stage of sperm development, especially at lag days 0-9 and 10-14 (all P < 0.05). Stratified analyses showed that the study pollutants (except CO) had a positive effect on semen concentration during the stage of sperm development, especially in spring and autumn, while a decreased total sperm number was associated with CO (all P < 0.05). However, joint associations of particulate and gaseous pollutants with semen quality parameters were not statistically significant (all P > 0.05).</p><p><strong>Conclusions: </strong>During all stages of sperm development, particulate and gaseous pollutants had individual negative impacts on sperm motility and semen volume, and these impacts were less pronounced in spring and autumn. Our findings highlight the importance and necessity of reducing the exposure to pollutants especially in the critical stage of sperm development to improve semen quality.</p>","PeriodicalId":13761,"journal":{"name":"International Archives of Occupational and Environmental Health","volume":null,"pages":null},"PeriodicalIF":2.6000,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Individual and joint associations of air pollutants exposure with semen quality: A retrospective longitudinal study in Wenzhou, China.\",\"authors\":\"Xuchao Dai, Guangyuan Liu, Chengshuang Pan, Feidi Li, Yawen Liu, Jiaxin Liu, Gang Chen, Mengqi Zhang, Qianjin Fei, Jiujia Zheng, Hong Huang, Zhigang Wu\",\"doi\":\"10.1007/s00420-024-02095-7\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Purpose: </strong>The impact of air pollution on semen quality has been confirmed, yet the joint effect remains unclear. We evaluate the individual and joint associations of particulate (PM<sub>2.5</sub> and PM<sub>10</sub>) and gaseous pollutants (NO<sub>2</sub>, SO<sub>2</sub>, O<sub>3</sub> and CO) with semen quality.</p><p><strong>Methods: </strong>We included 5,114 men in this study from 2014 to 2022. The individual and joint associations were measured by multiple linear regression models.</p><p><strong>Results: </strong>Sperm motility and semen volume were inversely associated with pollutant concentrations during every stage of sperm development, especially at lag days 0-9 and 10-14 (all P < 0.05). Stratified analyses showed that the study pollutants (except CO) had a positive effect on semen concentration during the stage of sperm development, especially in spring and autumn, while a decreased total sperm number was associated with CO (all P < 0.05). However, joint associations of particulate and gaseous pollutants with semen quality parameters were not statistically significant (all P > 0.05).</p><p><strong>Conclusions: </strong>During all stages of sperm development, particulate and gaseous pollutants had individual negative impacts on sperm motility and semen volume, and these impacts were less pronounced in spring and autumn. Our findings highlight the importance and necessity of reducing the exposure to pollutants especially in the critical stage of sperm development to improve semen quality.</p>\",\"PeriodicalId\":13761,\"journal\":{\"name\":\"International Archives of Occupational and Environmental Health\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":2.6000,\"publicationDate\":\"2024-10-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"International Archives of Occupational and Environmental Health\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1007/s00420-024-02095-7\",\"RegionNum\":3,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2024/7/26 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"Q2\",\"JCRName\":\"PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"International Archives of Occupational and Environmental Health","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1007/s00420-024-02095-7","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/7/26 0:00:00","PubModel":"Epub","JCR":"Q2","JCRName":"PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH","Score":null,"Total":0}
Individual and joint associations of air pollutants exposure with semen quality: A retrospective longitudinal study in Wenzhou, China.
Purpose: The impact of air pollution on semen quality has been confirmed, yet the joint effect remains unclear. We evaluate the individual and joint associations of particulate (PM2.5 and PM10) and gaseous pollutants (NO2, SO2, O3 and CO) with semen quality.
Methods: We included 5,114 men in this study from 2014 to 2022. The individual and joint associations were measured by multiple linear regression models.
Results: Sperm motility and semen volume were inversely associated with pollutant concentrations during every stage of sperm development, especially at lag days 0-9 and 10-14 (all P < 0.05). Stratified analyses showed that the study pollutants (except CO) had a positive effect on semen concentration during the stage of sperm development, especially in spring and autumn, while a decreased total sperm number was associated with CO (all P < 0.05). However, joint associations of particulate and gaseous pollutants with semen quality parameters were not statistically significant (all P > 0.05).
Conclusions: During all stages of sperm development, particulate and gaseous pollutants had individual negative impacts on sperm motility and semen volume, and these impacts were less pronounced in spring and autumn. Our findings highlight the importance and necessity of reducing the exposure to pollutants especially in the critical stage of sperm development to improve semen quality.
期刊介绍：
International Archives of Occupational and Environmental Health publishes Editorials, Review Articles, Original Articles, and Letters to the Editor. It welcomes any manuscripts dealing with occupational or ambient environmental problems, with a special interest in research at the interface of occupational health and clinical medicine. The scope ranges from Biological Monitoring to Dermatology, from Fibers and Dust to Human Toxicology, from Nanomaterials and Ultra-fine Dust to Night- and Shift Work, from Psycho-mental Distress and Burnout to Vibrations. A complete list of topics can be found on the right-hand side under For authors and editors.
In addition, all papers should be based on present-day standards and relate to:
-Clinical and epidemiological studies on morbidity and mortality
-Clinical epidemiological studies on the parameters relevant to the estimation of health risks
-Human experimental studies on environmental health effects. Animal experiments are only acceptable if relevant to pathogenic aspects.
-Methods for studying the topics mentioned above.
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