同时刺激眶上神经和精神神经后,健康人眨眼反射的变化。

IF 1.2 4区 医学 Q2 MEDICINE, GENERAL & INTERNAL
Turkish Journal of Medical Sciences Pub Date : 2024-02-12 eCollection Date: 2024-01-01 DOI:10.55730/1300-0144.5823
Ayşegül Gündüz, Tuba Cerrahoğlu Şirin, Pınar Bekdik Şirinocak, Tuba Akinci, Burcu Nuran Arkali, Fatma Candan, Meral E Kiziltan
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引用次数: 0

摘要

背景/目的:在这项研究中,我们研究了同时和不同步刺激两根三叉神经分支后的眨眼反射(BR)。材料与方法:我们进行了三组实验:记录眨眼反射反应一:我们进行了三组实验:在 18 名健康人中,分别记录了眶上神经刺激(SON)后、精神神经刺激(MN)后以及同时刺激 SON 和 MN(SON+MN)后的 BR 反应;在 7 名健康人中,记录了在不同刺激间隔(ISI)下,在 SON 之前的 MN(以引起 BR 反应的强度)后的 BR 反应;在不同刺激间隔(ISI)下,记录了在 SON 之前的 MN(以感觉阈值)后的 BR 反应。我们比较了早期和晚期反应的幅度:结果:同时刺激 SON+MN 后的 R1 波幅大于单次刺激相同分支后的反应。同时刺激后的 R2 和 R2c 曲线下面积(AUC)小于单次刺激后 R2 和 R2c AUC 的算术和。第二个实验提供了恢复兴奋性曲线。在第三步中,我们获得了对 R1 的促进和对晚期反应的抑制:结论:与单次刺激的算术总和相比,SON+MN 刺激会增加 R1 电路的兴奋性;但是,晚期反应的幅度并没有增强。因此,我们提供的证据表明,同时刺激会增强人体的 R1 回路,而后期反应的调节则表现出与成对 SON 刺激类似的恢复曲线。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Changes in blink reflex after simultaneous supraorbital and mental nerve stimulations in healthy subjects.

Background/aim: In this study, we investigated the blink reflex (BR) after simultaneous and asynchronous stimulation of two trigeminal nerve branches. The objective was to characterize the physiology of trigeminal and facial circuits.

Materials and methods: We performed three sets of experiments: recording BR response i. after supraorbital nerve stimulation (SON), after mental nerve stimulation (MN), and after simultaneous SON and MN stimulation (SON+MN) in 18 healthy individuals; ii. after MN (at an intensity eliciting BR response) preceding SON at various interstimulus intervals (ISIs) in seven healthy subjects; iii after MN (at sensory threshold) preceding SON at various ISIs. We compared the magnitudes of early and late responses.

Results: The R1 amplitude after simultaneous SON+MN stimulation was greater than responses after single stimulation of the same branches. After simultaneous stimulations, the R2 and R2c areas under the curve (AUC) were smaller than the arithmetic sums of R2 and R2c AUC obtained after single stimulations. The second experiment provided a recovery excitability curve. In the third step, we obtained facilitation of R1 and inhibition of late responses.

Conclusion: The SON+MN stimulation caused an increased R1 circuit excitability compared to the arithmetic sum of the single stimulations; however, magnitudes of late responses did not potentiate. Thus, we have provided evidence for R1 circuit enhancement by simultaneous stimulation in humans, whereas modulation of late responses exhibited a recovery curve similar to that shown for paired SON stimulation.

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来源期刊
Turkish Journal of Medical Sciences
Turkish Journal of Medical Sciences 医学-医学:内科
CiteScore
4.60
自引率
4.30%
发文量
143
审稿时长
3-8 weeks
期刊介绍: Turkish Journal of Medical sciences is a peer-reviewed comprehensive resource that provides critical up-to-date information on the broad spectrum of general medical sciences. The Journal intended to publish original medical scientific papers regarding the priority based on the prominence, significance, and timeliness of the findings. However since the audience of the Journal is not limited to any subspeciality in a wide variety of medical disciplines, the papers focusing on the technical  details of a given medical  subspeciality may not be evaluated for publication.
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