新型息肉取出袋可降低结肠息肉切除术中的息肉破碎率:一项单盲随机对照研究。

IF 2.5 3区 医学 Q2 GASTROENTEROLOGY & HEPATOLOGY
Jindong Chu, Cuiyun Ma, Min Min, Qian Bi, Wei Shen, Xueting Zhang, Hanqing Zhang, Aitong Li, Yan Liu, Zheng Lu
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引用次数: 0

摘要

目的:息肉碎裂会影响完整切除的确认。本研究的主要目的是评估新型息肉取出袋降低结肠息肉碎裂率的可行性:方法:招募患有 5-15 毫米结肠息肉的患者,按 1:1 的比例随机分为两组。息肉切除后,治疗组患者的息肉通过新型息肉取出袋取出,无需穿越器械通道,而对照组患者的息肉则通过器械通道收集,将息肉捕捉器连接到器械通道口,然后进行抽吸:2022 年 1 月至 7 月,共对 225 名患者进行了资格评估。结果:从 2022 年 1 月到 7 月,共有 225 名患者接受了资格评估,其中包括 204 名患者,另有 7 名患者的样本未被提取。治疗组的息肉破碎率明显低于对照组(3.0% [3/100] vs. 17.5% [17/97],P = 0.001)。治疗组和对照组的取材失败率无明显差异(2.0% [2/102] vs. 4.9% [5/102],P = 0.442)。治疗组的结肠镜插入次数少于对照组(102 次对 110 次),但差异不显著(P = 0.065)。随访期间未发现明显的不良反应:这项研究表明,息肉摘除袋在降低摘除息肉的碎裂率方面是安全可行的:该研究已在 ClinicalTrials.gov 注册(NCT05189912,1/12/2021)。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

A novel polyp retrieval bag reduces the polyp fragmentation rate in colon polypectomy: a single-blind randomized controlled study.

A novel polyp retrieval bag reduces the polyp fragmentation rate in colon polypectomy: a single-blind randomized controlled study.

Purpose: The fragmentation of polyps affects complete resection confirmation. The primary aim of this study was to assess the feasibility of a novel polyp retrieval bag for reducing the fragmentation rate of colon polyps.

Methods: Patients with a 5-15 mm colon polyp were recruited and randomized into two groups at a 1:1 ratio. After polyp resection, polyps obtained from patients in the treatment group were extracted via a novel polyp retrieval bag without traversing the instrument channel, whereas polyps obtained from patients in the control group were collected through the instrument channel, attaching the polyp trap to the instrument channel port, and applying suction.

Results: From January to July 2022, 225 patients were assessed for eligibility. The study participants included 204 patients, and seven patients whose samples were not retrieved were excluded. Polyp fragmentation was significantly lower in the treatment group than in the control group (3.0% [3/100] vs. 17.5% [17/97], P = 0.001). The retrieval failure rates in the treatment group and control group were not significantly different (2.0% [2/102] vs. 4.9% [5/102], P = 0.442). There were fewer colonoscope insertions in the treatment group than in the control group (102 vs. 110), but a significant difference was not present (P = 0.065). No significant adverse events were observed during the follow-up.

Conclusions: This study demonstrated that the polyp retrieval bag was safe and feasible for reducing the fragmentation rate of retrieved polyps.

Trial registration: The study was registered at ClinicalTrials.gov (NCT05189912, 1/12/2021).

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来源期刊
CiteScore
4.90
自引率
3.60%
发文量
206
审稿时长
3-8 weeks
期刊介绍: The International Journal of Colorectal Disease, Clinical and Molecular Gastroenterology and Surgery aims to publish novel and state-of-the-art papers which deal with the physiology and pathophysiology of diseases involving the entire gastrointestinal tract. In addition to original research articles, the following categories will be included: reviews (usually commissioned but may also be submitted), case reports, letters to the editor, and protocols on clinical studies. The journal offers its readers an interdisciplinary forum for clinical science and molecular research related to gastrointestinal disease.
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