RNase R 与 PNPase：选择最适合环境适应的外切核酸酶。

IF 2.6 3区生物学 Q3 BIOCHEMISTRY & MOLECULAR BIOLOGY

Extremophiles Pub Date : 2024-07-25 DOI:10.1007/s00792-024-01350-6

Theetha L Pavankumar

{"title":"RNase R 与 PNPase：选择最适合环境适应的外切核酸酶。","authors":"Theetha L Pavankumar","doi":"10.1007/s00792-024-01350-6","DOIUrl":null,"url":null,"abstract":"3' → 5' exoribonucleases play a critical role in many aspects of RNA metabolism. RNase R, PNPase, and RNase II are the major contributors to RNA processing, maturation, and quality control in bacteria. Bacteria don't seem to have dedicated RNA degradation machineries to process different classes of RNAs. Under different environmental and physiological conditions, their roles can be redundant and sometimes overlapping. Here, I discuss why PNPase and RNase R may have switched their physiological roles in some bacterial species to adapt to environmental conditions, despite being biochemically distinct exoribonucleases.","PeriodicalId":12302,"journal":{"name":"Extremophiles","volume":null,"pages":null},"PeriodicalIF":2.6000,"publicationDate":"2024-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"RNase R vs. PNPase: selecting the best-suited exoribonuclease for environmental adaptation.\",\"authors\":\"Theetha L Pavankumar\",\"doi\":\"10.1007/s00792-024-01350-6\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"3' → 5' exoribonucleases play a critical role in many aspects of RNA metabolism. RNase R, PNPase, and RNase II are the major contributors to RNA processing, maturation, and quality control in bacteria. Bacteria don't seem to have dedicated RNA degradation machineries to process different classes of RNAs. Under different environmental and physiological conditions, their roles can be redundant and sometimes overlapping. Here, I discuss why PNPase and RNase R may have switched their physiological roles in some bacterial species to adapt to environmental conditions, despite being biochemically distinct exoribonucleases.\",\"PeriodicalId\":12302,\"journal\":{\"name\":\"Extremophiles\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":2.6000,\"publicationDate\":\"2024-07-25\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Extremophiles\",\"FirstCategoryId\":\"99\",\"ListUrlMain\":\"https://doi.org/10.1007/s00792-024-01350-6\",\"RegionNum\":3,\"RegionCategory\":\"生物学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"BIOCHEMISTRY & MOLECULAR BIOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Extremophiles","FirstCategoryId":"99","ListUrlMain":"https://doi.org/10.1007/s00792-024-01350-6","RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"BIOCHEMISTRY & MOLECULAR BIOLOGY","Score":null,"Total":0}

引用次数: 0

摘要

3' → 5' 外切核酸酶在 RNA 代谢的许多方面都发挥着关键作用。RNase R、PNPase 和 RNase II 是细菌中 RNA 处理、成熟和质量控制的主要贡献者。细菌似乎没有专门的 RNA 降解机制来处理不同类别的 RNA。在不同的环境和生理条件下，它们的作用可能是多余的，有时甚至是重叠的。在这里，我将讨论为什么尽管PNPase和RNase R是生化上不同的外切核酸酶，但在某些细菌物种中，它们的生理作用可能会发生转换，以适应环境条件。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

RNase R vs. PNPase: selecting the best-suited exoribonuclease for environmental adaptation.

查看原文本刊更多论文

RNase R vs. PNPase: selecting the best-suited exoribonuclease for environmental adaptation.

3' → 5' exoribonucleases play a critical role in many aspects of RNA metabolism. RNase R, PNPase, and RNase II are the major contributors to RNA processing, maturation, and quality control in bacteria. Bacteria don't seem to have dedicated RNA degradation machineries to process different classes of RNAs. Under different environmental and physiological conditions, their roles can be redundant and sometimes overlapping. Here, I discuss why PNPase and RNase R may have switched their physiological roles in some bacterial species to adapt to environmental conditions, despite being biochemically distinct exoribonucleases.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Extremophiles 生物-生化与分子生物学

CiteScore

6.80

自引率

6.90%

发文量

审稿时长

2 months

期刊介绍： Extremophiles features original research articles, reviews, and method papers on the biology, molecular biology, structure, function, and applications of microbial life at high or low temperature, pressure, acidity, alkalinity, salinity, or desiccation; or in the presence of organic solvents, heavy metals, normally toxic substances, or radiation.