肺栓塞:意大利托斯卡纳十二年历史序列中的发病率和结果(2010-2021 年)。

IF 1.5 Q3 HEALTH CARE SCIENCES & SERVICES
Gabriele Cerini, Carla Lunetta, Claudia Szasz, Leonardo Misuraca, Fabrizio Gemmi, Marisa Carluccio, Chiara Lorini, Guglielmo Bonaccorsi, Silvia Forni
{"title":"肺栓塞:意大利托斯卡纳十二年历史序列中的发病率和结果(2010-2021 年)。","authors":"Gabriele Cerini, Carla Lunetta, Claudia Szasz, Leonardo Misuraca, Fabrizio Gemmi, Marisa Carluccio, Chiara Lorini, Guglielmo Bonaccorsi, Silvia Forni","doi":"10.7416/ai.2024.2649","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Pulmonary embolism poses a global health concern. Administrative databases serve as valuable sources for broad epidemiological studies on the prevalence and incidence of major diagnoses or diseases. The primary scope is to provide up-to-date insights into Pulmonary Embolism incidence trends, examining shifts in management and outcomes.</p><p><strong>Design: </strong>This retrospective observational study examines a 12-year dataset from hospitals in the Tuscany Region, covering the first two years of the Covid-19 pandemic.</p><p><strong>Methods: </strong>Administrative data from residents aged 18 and older discharged from hospital between 2010 and 2021 were used for the analysis.</p><p><strong>Results: </strong>Hospitalized pulmonary embolism incidence slightly declined from 2010 to 2019 (64.7 to 60.9 x 100,000; p=0.152). Males under 75 showed a higher incidence rate, while females had higher incidence rates in older age groups. In-hospital and 30-day mortality decreased from 2010 to 2019 (p=0.001 and 0.020 respectively). In 2020, 30-day mortality increased (12.4% vs 10.1%, p=0.029), while in-hospital mortality remained stable. One-year mortality was stable from 2010-2019 but increased in 2020 (32.6% vs 29.4%, p=0.037). Considering the multivariable model, one-year mortality is significantly associated with sex, age, and comorbidities.</p><p><strong>Conclusions: </strong>Our study shows that Pulmonary Embolism persists as a relevant burden in Tuscany region, but with improvements in management over the past decade and a decisive change in pharmacological treatment. Gender-related differences emerge, highlighting the need for a gender-specific healthcare approach.</p>","PeriodicalId":7999,"journal":{"name":"Annali di igiene : medicina preventiva e di comunita","volume":null,"pages":null},"PeriodicalIF":1.5000,"publicationDate":"2024-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Pulmonary embolism: incidence and outcomes in a twelve-year historical series, in Tuscany - Italy (2010-2021).\",\"authors\":\"Gabriele Cerini, Carla Lunetta, Claudia Szasz, Leonardo Misuraca, Fabrizio Gemmi, Marisa Carluccio, Chiara Lorini, Guglielmo Bonaccorsi, Silvia Forni\",\"doi\":\"10.7416/ai.2024.2649\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>Pulmonary embolism poses a global health concern. Administrative databases serve as valuable sources for broad epidemiological studies on the prevalence and incidence of major diagnoses or diseases. The primary scope is to provide up-to-date insights into Pulmonary Embolism incidence trends, examining shifts in management and outcomes.</p><p><strong>Design: </strong>This retrospective observational study examines a 12-year dataset from hospitals in the Tuscany Region, covering the first two years of the Covid-19 pandemic.</p><p><strong>Methods: </strong>Administrative data from residents aged 18 and older discharged from hospital between 2010 and 2021 were used for the analysis.</p><p><strong>Results: </strong>Hospitalized pulmonary embolism incidence slightly declined from 2010 to 2019 (64.7 to 60.9 x 100,000; p=0.152). Males under 75 showed a higher incidence rate, while females had higher incidence rates in older age groups. In-hospital and 30-day mortality decreased from 2010 to 2019 (p=0.001 and 0.020 respectively). In 2020, 30-day mortality increased (12.4% vs 10.1%, p=0.029), while in-hospital mortality remained stable. One-year mortality was stable from 2010-2019 but increased in 2020 (32.6% vs 29.4%, p=0.037). Considering the multivariable model, one-year mortality is significantly associated with sex, age, and comorbidities.</p><p><strong>Conclusions: </strong>Our study shows that Pulmonary Embolism persists as a relevant burden in Tuscany region, but with improvements in management over the past decade and a decisive change in pharmacological treatment. Gender-related differences emerge, highlighting the need for a gender-specific healthcare approach.</p>\",\"PeriodicalId\":7999,\"journal\":{\"name\":\"Annali di igiene : medicina preventiva e di comunita\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":1.5000,\"publicationDate\":\"2024-07-24\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Annali di igiene : medicina preventiva e di comunita\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.7416/ai.2024.2649\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"HEALTH CARE SCIENCES & SERVICES\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Annali di igiene : medicina preventiva e di comunita","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.7416/ai.2024.2649","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"HEALTH CARE SCIENCES & SERVICES","Score":null,"Total":0}
引用次数: 0

摘要

背景:肺栓塞是一个全球性的健康问题。行政数据库是对主要诊断或疾病的流行率和发病率进行广泛流行病学研究的宝贵资料来源。研究的主要范围是提供有关肺栓塞发病趋势的最新见解,研究管理和结果的变化:这项回顾性观察研究检查了托斯卡纳地区医院 12 年的数据集,涵盖了 Covid-19 大流行的头两年:分析采用的是 2010 年至 2021 年期间 18 岁及以上出院居民的管理数据:住院肺栓塞发病率从2010年到2019年略有下降(64.7到60.9 x 100,000;P=0.152)。75岁以下的男性发病率较高,而女性在较高年龄段的发病率较高。从 2010 年到 2019 年,住院死亡率和 30 天死亡率有所下降(p=0.001 和 0.020)。2020年,30天死亡率上升(12.4% vs 10.1%,p=0.029),而院内死亡率保持稳定。2010-2019年,一年死亡率保持稳定,但2020年有所上升(32.6% vs 29.4%,p=0.037)。考虑到多变量模型,一年死亡率与性别、年龄和合并症显著相关:我们的研究表明,肺栓塞仍然是托斯卡纳地区的一个相关负担,但在过去十年中,管理有所改善,药物治疗也发生了决定性的变化。与性别有关的差异显现出来,这突出表明需要采取针对不同性别的医疗保健方法。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Pulmonary embolism: incidence and outcomes in a twelve-year historical series, in Tuscany - Italy (2010-2021).

Background: Pulmonary embolism poses a global health concern. Administrative databases serve as valuable sources for broad epidemiological studies on the prevalence and incidence of major diagnoses or diseases. The primary scope is to provide up-to-date insights into Pulmonary Embolism incidence trends, examining shifts in management and outcomes.

Design: This retrospective observational study examines a 12-year dataset from hospitals in the Tuscany Region, covering the first two years of the Covid-19 pandemic.

Methods: Administrative data from residents aged 18 and older discharged from hospital between 2010 and 2021 were used for the analysis.

Results: Hospitalized pulmonary embolism incidence slightly declined from 2010 to 2019 (64.7 to 60.9 x 100,000; p=0.152). Males under 75 showed a higher incidence rate, while females had higher incidence rates in older age groups. In-hospital and 30-day mortality decreased from 2010 to 2019 (p=0.001 and 0.020 respectively). In 2020, 30-day mortality increased (12.4% vs 10.1%, p=0.029), while in-hospital mortality remained stable. One-year mortality was stable from 2010-2019 but increased in 2020 (32.6% vs 29.4%, p=0.037). Considering the multivariable model, one-year mortality is significantly associated with sex, age, and comorbidities.

Conclusions: Our study shows that Pulmonary Embolism persists as a relevant burden in Tuscany region, but with improvements in management over the past decade and a decisive change in pharmacological treatment. Gender-related differences emerge, highlighting the need for a gender-specific healthcare approach.

求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
Annali di igiene : medicina preventiva e di comunita
Annali di igiene : medicina preventiva e di comunita HEALTH CARE SCIENCES & SERVICES-
CiteScore
3.40
自引率
0.00%
发文量
69
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信