Rafael Silva Lemos, Livia Guerreiro de Barros Bentes, Maria Eduarda Dos Santos Lopes Vasconcelos, Daniela Ferreira Tramontin, Luís Vinícius Pires da Costa, Antonio Leonardo Jatahi Cavalcanti Pimentel, Nayara Pontes de Araújo, Mariseth Carvalho de Andrade, Danusa Neves Somensi, Rui Sérgio Monteiro de Barros
{"title":"外周节段性神经缺失重建中的端侧神经出血术：一项实验研究。","authors":"Rafael Silva Lemos, Livia Guerreiro de Barros Bentes, Maria Eduarda Dos Santos Lopes Vasconcelos, Daniela Ferreira Tramontin, Luís Vinícius Pires da Costa, Antonio Leonardo Jatahi Cavalcanti Pimentel, Nayara Pontes de Araújo, Mariseth Carvalho de Andrade, Danusa Neves Somensi, Rui Sérgio Monteiro de Barros","doi":"10.1590/acb394024","DOIUrl":null,"url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the effects on peripheral neural regeneration of the end-to-side embracing repair technique compared to the autograft repair technique in Wistar rats.</p><p><strong>Methods: </strong>Fifteen male Wistar rats were divided into three groups with five animals each: denervated group (GD), autograft group (GA), and embracing group (EG). For the evaluation, the grasping test, electroneuromyography (ENMG), and muscle weight assessment were used.</p><p><strong>Results: </strong>Muscle weight assessment and ENMG did not show significant neural regeneration at the end of 12 weeks in the DG and GE groups, but only in GA. The grasping test showed an increase in strength between the surgery and the fourth week in all groups, and only the GA maintained this trend until the 12th week.</p><p><strong>Conclusions: </strong>The present study indicates that the neural regeneration observed in the end-to-side embracing neurorrhaphy technique, in the repair of segmental neural loss, is inferior to autograft repair in Wistar rats.</p>","PeriodicalId":93850,"journal":{"name":"Acta cirurgica brasileira","volume":"39 ","pages":"e394024"},"PeriodicalIF":0.0000,"publicationDate":"2024-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11262751/pdf/","citationCount":"0","resultStr":"{\"title\":\"End-to-side neurorrhaphy in the reconstruction of peripheral segmental neural loss: an experimental study.\",\"authors\":\"Rafael Silva Lemos, Livia Guerreiro de Barros Bentes, Maria Eduarda Dos Santos Lopes Vasconcelos, Daniela Ferreira Tramontin, Luís Vinícius Pires da Costa, Antonio Leonardo Jatahi Cavalcanti Pimentel, Nayara Pontes de Araújo, Mariseth Carvalho de Andrade, Danusa Neves Somensi, Rui Sérgio Monteiro de Barros\",\"doi\":\"10.1590/acb394024\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Purpose: </strong>To evaluate the effects on peripheral neural regeneration of the end-to-side embracing repair technique compared to the autograft repair technique in Wistar rats.</p><p><strong>Methods: </strong>Fifteen male Wistar rats were divided into three groups with five animals each: denervated group (GD), autograft group (GA), and embracing group (EG). For the evaluation, the grasping test, electroneuromyography (ENMG), and muscle weight assessment were used.</p><p><strong>Results: </strong>Muscle weight assessment and ENMG did not show significant neural regeneration at the end of 12 weeks in the DG and GE groups, but only in GA. The grasping test showed an increase in strength between the surgery and the fourth week in all groups, and only the GA maintained this trend until the 12th week.</p><p><strong>Conclusions: </strong>The present study indicates that the neural regeneration observed in the end-to-side embracing neurorrhaphy technique, in the repair of segmental neural loss, is inferior to autograft repair in Wistar rats.</p>\",\"PeriodicalId\":93850,\"journal\":{\"name\":\"Acta cirurgica brasileira\",\"volume\":\"39 \",\"pages\":\"e394024\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2024-07-22\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11262751/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Acta cirurgica brasileira\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1590/acb394024\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2024/1/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Acta cirurgica brasileira","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1590/acb394024","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/1/1 0:00:00","PubModel":"eCollection","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
摘要
目的：与自体移植修复技术相比，评估端侧拥抱修复技术对 Wistar 大鼠外周神经再生的影响：将 15 只雄性 Wistar 大鼠分为三组，每组 5 只：去神经支配组（GD）、自体移植组（GA）和环抱组（EG）。评估方法包括抓握试验、电肌电图（ENMG）和肌肉重量评估：结果：在 12 周结束时，肌肉重量评估和 ENMG 在 DG 组和 GE 组未显示出明显的神经再生，仅在 GA 组显示出神经再生。抓握试验显示，从手术到第四周，所有组的力量都有所增加，只有 GA 组在第 12 周前保持了这一趋势：本研究表明，在 Wistar 大鼠节段性神经缺失的修复中，端侧环抱神经切除术的神经再生效果不如自体移植修复术。
End-to-side neurorrhaphy in the reconstruction of peripheral segmental neural loss: an experimental study.
Purpose: To evaluate the effects on peripheral neural regeneration of the end-to-side embracing repair technique compared to the autograft repair technique in Wistar rats.
Methods: Fifteen male Wistar rats were divided into three groups with five animals each: denervated group (GD), autograft group (GA), and embracing group (EG). For the evaluation, the grasping test, electroneuromyography (ENMG), and muscle weight assessment were used.
Results: Muscle weight assessment and ENMG did not show significant neural regeneration at the end of 12 weeks in the DG and GE groups, but only in GA. The grasping test showed an increase in strength between the surgery and the fourth week in all groups, and only the GA maintained this trend until the 12th week.
Conclusions: The present study indicates that the neural regeneration observed in the end-to-side embracing neurorrhaphy technique, in the repair of segmental neural loss, is inferior to autograft repair in Wistar rats.
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
