化妆品中使用的乙烯基吡咯烷酮聚合物的安全性评估。

IF 1.2 4区医学 Q4 PHARMACOLOGY & PHARMACY

International Journal of Toxicology Pub Date : 2024-10-01 Epub Date: 2024-07-24 DOI:10.1177/10915818241267203

Wilbur Johnson, Wilma F Bergfeld, Donald V Belsito, Ronald A Hill, Curtis D Klaassen, Daniel C Liebler, James G Marks, Ronald C Shank, Thomas J Slaga, Paul W Snyder, Monice Fiume, Bart Heldreth

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引用次数: 0

摘要

化妆品成分安全专家小组（以下简称 "专家小组"）审查了 30 种用于化妆品的乙烯基吡咯烷酮聚合物的安全性；据报告，这些成分中的大多数都具有成膜剂的化妆品功能。专家小组审查了与这些成分的安全性相关的数据，并确定 27 种乙烯基吡咯烷酮聚合物在化妆品中的使用是安全的，其目前的使用方法和浓度在安全性评估中有所描述。评估小组还得出结论认为，现有数据不足以确定 3 种乙烯基吡咯烷酮聚合物（均为聚氨酯）在化妆品配方的预期使用条件下是安全的。

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Safety Assessment of Vinylpyrrolidone Polymers as Used in Cosmetics.

The Expert Panel for Cosmetic Ingredient Safety (Panel) reviewed the safety of 30 vinylpyrrolidone polymers as used in cosmetic products; most of these ingredients have the reported cosmetic function of film former in common. The Panel reviewed data relevant to the safety of these ingredients, and determined that 27 vinylpyrrolidone polymers are safe in cosmetics in the present practices of use and concentration described in the safety assessment. The Panel also concluded that the available data are insufficient to make a determination that 3 vinylpyrrolidone polymers (all urethanes) are safe under the intended conditions of use in cosmetic formulations.

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来源期刊

International Journal of Toxicology 医学-毒理学

CiteScore

3.40

自引率

4.50%

发文量

审稿时长

4.5 months

期刊介绍： The International Journal of Toxicology publishes timely, peer-reviewed papers on current topics important to toxicologists. Six bi-monthly issues cover a wide range of topics, including contemporary issues in toxicology, safety assessments, novel approaches to toxicological testing, mechanisms of toxicity, biomarkers, and risk assessment. The Journal also publishes invited reviews on contemporary topics, and features articles based on symposia. In addition, supplemental issues are routinely published on various special topics, including three supplements devoted to contributions from the Cosmetic Review Expert Panel.