治疗使用 ECMO 的儿科患者药物难治性颅内压升高:示例病例。

IF 1.3 4区 医学 Q4 CLINICAL NEUROLOGY
Child's Nervous System Pub Date : 2024-11-01 Epub Date: 2024-07-24 DOI:10.1007/s00381-024-06549-8
Tirone Young, Bahie Ezzat, Noah Nichols, Scott Aydin, Peter Pastuszko, Peter F Morgenstern
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引用次数: 0

摘要

目的:我们展示了需要进行神经外科手术的体外膜肺氧合(ECMO)治疗儿科患者的复杂管理,重点是全身抗凝、心脏功能和药物难治性颅内压(ICP):一名患有法洛氏四联症的 3.5 岁女性在术后心脏骤停后出现严重缺血性脑水肿,需要接受 ECMO 治疗。我们对该病例以及另外四例在使用 ECMO 时需要进行神经外科手术的儿童进行了研究:结果:对主要病例进行紧急神经外科干预后,患儿病情明显好转,这凸显了管理 ECMO 引起的抗凝和紧急神经外科需求之间的微妙平衡。其他病例的治疗结果各不相同,突显了护理这些重症患者所面临的挑战:结论:成功管理需要 ECMO 支持和神经外科干预的患儿需要周到的多学科护理。本报告说明了此类决策中的一些细微差别,并展示了通往良好结果的一条潜在途径。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Managing medically refractory elevated intracranial pressure in a pediatric patient on ECMO: illustrative case.

Managing medically refractory elevated intracranial pressure in a pediatric patient on ECMO: illustrative case.

Purpose: We demonstrate the complexities of managing pediatric patients on extracorporeal membrane oxygenation (ECMO) therapy requiring neurosurgery, focusing on systemic anticoagulation, cardiac function, and medically refractory intracranial pressure (ICP).

Methods: A 3.5-year-old female with Tetralogy of Fallot developed severe ischemic cerebral edema following post-operative cardiac arrest and required ECMO. This case, along with four additional cases of children requiring neurosurgery while on ECMO, was examined.

Results: Emergency neurosurgical intervention in the primary case led to significant improvement, highlighting the delicate balance between managing ECMO-induced anticoagulation and urgent neurosurgical needs. The additional cases had variable outcomes, emphasizing the challenges of caring for these critically ill patients.

Conclusion: Successful management of children requiring ECMO support and neurosurgical intervention requires thoughtful multidisciplinary care. This report illustrates some of the nuances in such decision-making, and demonstrates one potential path to a good outcome.

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来源期刊
Child's Nervous System
Child's Nervous System 医学-临床神经学
CiteScore
3.00
自引率
7.10%
发文量
322
审稿时长
3 months
期刊介绍: The journal has been expanded to encompass all aspects of pediatric neurosciences concerning the developmental and acquired abnormalities of the nervous system and its coverings, functional disorders, epilepsy, spasticity, basic and clinical neuro-oncology, rehabilitation and trauma. Global pediatric neurosurgery is an additional field of interest that will be considered for publication in the journal.
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