角化过度挠曲性红斑的组织学多样性--颗粒状副角化病之外？

IF 2.2 4区医学 Q2 DERMATOLOGY

Australasian Journal of Dermatology Pub Date : 2024-07-24 DOI:10.1111/ajd.14349

Anna Luo, Fergus Oliver, Harriet Kennedy

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引用次数: 0

摘要

角化过度性挠曲红斑"（HFE）与 "粒状角化病"（GP）同义，用于描述与苯扎氯铵等接触性因素有关的鳞状典型皮疹。然而，临床上的 HFE 也可能没有典型的 GP 组织学模式。我们对 10 名临床诊断为 HFE 的患者的皮肤活检进行了复查。我们提出了组织病理学特征的发展过程。在高度怀疑的情况下，不存在组织学 GP 不应排除 HFE 的临床诊断。

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Histological diversity in hyperkeratotic flexural erythema-Beyond granular parakeratosis?

The term 'hyperkeratotic flexural erythema' (HFE) has been used synonymously with granular parakeratosis (GP), to describe a scaly, typically intertriginous rash associated with contact factors such as benzalkonium chloride. However, clinical HFE can occur without the classical GP histological pattern. We reviewed skin biopsies from 10 patients with clinically diagnosed HFE. A progression of histopathological features is suggested. The absence of histological GP should not exclude the clinical diagnosis of HFE when there is a high index of suspicion.

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来源期刊

Australasian Journal of Dermatology 医学-皮肤病学

CiteScore

3.20

自引率

5.00%

发文量

186

审稿时长

6-12 weeks

期刊介绍： Australasian Journal of Dermatology is the official journal of the Australasian College of Dermatologists and the New Zealand Dermatological Society, publishing peer-reviewed, original research articles, reviews and case reports dealing with all aspects of clinical practice and research in dermatology. Clinical presentations, medical and physical therapies and investigations, including dermatopathology and mycology, are covered. Short articles may be published under the headings ‘Signs, Syndromes and Diagnoses’, ‘Dermatopathology Presentation’, ‘Vignettes in Contact Dermatology’, ‘Surgery Corner’ or ‘Letters to the Editor’.