{"title":"补充类黄酮对多囊卵巢综合征有益：系统回顾与元分析》。","authors":"Yiting Jiang, Weihuan Hu, Hanyue Zhu, Chang Liu, Fan Qu, Jue Zhou","doi":"10.1093/nutrit/nuae101","DOIUrl":null,"url":null,"abstract":"<p><strong>Context: </strong>Polycystic ovary syndrome (PCOS) is a prevalent hormonal imbalance that predominantly affects women in their reproductive years. Previous studies have yielded conflicting conclusions.</p><p><strong>Objective: </strong>This is an updated meta-analysis aiming to explore the connection between flavonoid supplementation and PCOS.</p><p><strong>Data sources: </strong>Seven databases were searched: Cochrane Library, PubMed, Web of Science, Embase, Wanfang, China Science and Technology Journal, and China National Knowledge Infrastructure, spanning from their inception to April 15, 2024.</p><p><strong>Data extraction: </strong>Two authors independently searched the databases using the search terms.</p><p><strong>Data analysis: </strong>Following strict inclusion criteria, 8 papers were ultimately included. This updated meta-analysis suggests that flavonoid supplementation could enhance follicular development, promote the proliferation and differentiation of follicular granulosa cells, elevate estradiol levels, and mitigate testosterone, C-reactive protein, and ovarian index levels.</p><p><strong>Conclusion: </strong>This analysis suggests that dietary flavonoids could potentially alleviate symptoms associated with PCOS.</p><p><strong>Systematic review registration: </strong>PROSPERO registration no. CRD42022382912.</p>","PeriodicalId":19469,"journal":{"name":"Nutrition reviews","volume":" ","pages":""},"PeriodicalIF":5.9000,"publicationDate":"2024-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Flavonoid Supplementation Is Beneficial for Polycystic Ovary Syndrome: A Systematic Review and Meta-analysis.\",\"authors\":\"Yiting Jiang, Weihuan Hu, Hanyue Zhu, Chang Liu, Fan Qu, Jue Zhou\",\"doi\":\"10.1093/nutrit/nuae101\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Context: </strong>Polycystic ovary syndrome (PCOS) is a prevalent hormonal imbalance that predominantly affects women in their reproductive years. Previous studies have yielded conflicting conclusions.</p><p><strong>Objective: </strong>This is an updated meta-analysis aiming to explore the connection between flavonoid supplementation and PCOS.</p><p><strong>Data sources: </strong>Seven databases were searched: Cochrane Library, PubMed, Web of Science, Embase, Wanfang, China Science and Technology Journal, and China National Knowledge Infrastructure, spanning from their inception to April 15, 2024.</p><p><strong>Data extraction: </strong>Two authors independently searched the databases using the search terms.</p><p><strong>Data analysis: </strong>Following strict inclusion criteria, 8 papers were ultimately included. This updated meta-analysis suggests that flavonoid supplementation could enhance follicular development, promote the proliferation and differentiation of follicular granulosa cells, elevate estradiol levels, and mitigate testosterone, C-reactive protein, and ovarian index levels.</p><p><strong>Conclusion: </strong>This analysis suggests that dietary flavonoids could potentially alleviate symptoms associated with PCOS.</p><p><strong>Systematic review registration: </strong>PROSPERO registration no. CRD42022382912.</p>\",\"PeriodicalId\":19469,\"journal\":{\"name\":\"Nutrition reviews\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":5.9000,\"publicationDate\":\"2024-07-22\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Nutrition reviews\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1093/nutrit/nuae101\",\"RegionNum\":2,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"NUTRITION & DIETETICS\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Nutrition reviews","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1093/nutrit/nuae101","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"NUTRITION & DIETETICS","Score":null,"Total":0}
引用次数: 0
摘要
背景：多囊卵巢综合征（PCOS）是一种常见的内分泌失调症，主要影响育龄妇女。以往的研究得出了相互矛盾的结论：这是一项最新的荟萃分析，旨在探讨类黄酮补充剂与多囊卵巢综合征之间的联系：数据来源：检索了七个数据库：Cochrane图书馆、PubMed、Web of Science、Embase、万方、中国科技期刊和中国国家知识基础设施，时间跨度从开始到2024年4月15日：数据分析：根据严格的纳入标准，最终纳入了 8 篇论文。这项最新的荟萃分析表明，补充类黄酮可促进卵泡发育，促进卵泡颗粒细胞的增殖和分化，提高雌二醇水平，降低睾酮、C反应蛋白和卵巢指数水平：这项分析表明，膳食中的类黄酮有可能减轻多囊卵巢综合症的相关症状：系统综述注册：PROSPERO 注册编号CRD42022382912。
Flavonoid Supplementation Is Beneficial for Polycystic Ovary Syndrome: A Systematic Review and Meta-analysis.
Context: Polycystic ovary syndrome (PCOS) is a prevalent hormonal imbalance that predominantly affects women in their reproductive years. Previous studies have yielded conflicting conclusions.
Objective: This is an updated meta-analysis aiming to explore the connection between flavonoid supplementation and PCOS.
Data sources: Seven databases were searched: Cochrane Library, PubMed, Web of Science, Embase, Wanfang, China Science and Technology Journal, and China National Knowledge Infrastructure, spanning from their inception to April 15, 2024.
Data extraction: Two authors independently searched the databases using the search terms.
Data analysis: Following strict inclusion criteria, 8 papers were ultimately included. This updated meta-analysis suggests that flavonoid supplementation could enhance follicular development, promote the proliferation and differentiation of follicular granulosa cells, elevate estradiol levels, and mitigate testosterone, C-reactive protein, and ovarian index levels.
Conclusion: This analysis suggests that dietary flavonoids could potentially alleviate symptoms associated with PCOS.
期刊介绍：
Nutrition Reviews is a highly cited, monthly, international, peer-reviewed journal that specializes in the publication of authoritative and critical literature reviews on current and emerging topics in nutrition science, food science, clinical nutrition, and nutrition policy. Readers of Nutrition Reviews include nutrition scientists, biomedical researchers, clinical and dietetic practitioners, and advanced students of nutrition.
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