A 型肉毒毒素神经调节剂在面瘫同步运动治疗中的作用。

IF 16.4 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Accounts of Chemical Research Pub Date : 2024-08-27 DOI:10.1055/a-2370-2426

Asalet Yener, Vikas Acharya, Peter Andrews, Catherine Meller, Eamon Shamil

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引用次数: 0

摘要

面神经麻痹指的是面神经神经支配导致面部动画和表情困难。面部同步运动是面神经轴突受损后复杂的病理性神经再生的结果。面瘫患者的同步运动障碍可通过面部神经肌肉康复治疗、肉毒杆菌毒素神经调节剂和手术治疗来控制。肉毒杆菌毒素 A 可作为其他治疗方案的辅助手段来控制同步运动。本文将探讨 A 型肉毒毒素在治疗面瘫协同运动中的作用，包括临床评估、注射位置（目标肌肉）、剂量、治疗间隔和长期效果。它还将包括手术治疗方案。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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The Role of Botulinum Toxin A Neuromodulator in the Management of Synkinesis in Facial Palsy.

Facial palsy describes the denervation of the facial nerve leading to difficulty in facial animation and expression. Facial synkinesis is the result of complex pathological nerve regeneration following damage to the facial nerve axons. Synkinesis in facial palsy can be managed using facial neuromuscular rehabilitation, botulinum toxin neuromodulators, and surgical treatment options. Botulinum toxin A can be used as an adjunct to other treatment options to manage synkinesis. This article will explore the role of botulinum toxin A in the management of synkinesis in facial palsy including the clinical assessment, injection location (muscles targeted), dosages, treatment interval, and long-term results. It will also include surgical management options.

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来源期刊

Accounts of Chemical Research 化学-化学综合

CiteScore

31.40

自引率

1.10%

发文量

312

审稿时长

2 months

期刊介绍： Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.