用于生物应用的基于蓝素的近红外荧光探针的研究进展。

IF 2.6 4区生物学 Q3 BIOCHEMISTRY & MOLECULAR BIOLOGY

ChemBioChem Pub Date : 2024-07-22 DOI:10.1002/cbic.202400467

Chusen Huang, Jigao Xuan, Jiajun Yu

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引用次数: 0

摘要

基于青素的近红外（NIR）荧光探针因其本底荧光干扰小、组织穿透深、灵敏度高、对生物样本的光损伤小等特点，在生物应用中发挥着重要作用。它们被广泛应用于分子识别、医疗诊断、生物分子检测和生物成像等领域。在此，我们将综述用于检测 pH 值、细胞、肿瘤的氰基近红外荧光探针的最新进展及其在光热疗法（PTT）和光动力疗法（PDT）中的应用。

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Research Progress of Cyanine-based Near-Infrared Fluorescent Probes for Biological Application.

Cyanine-based near-infrared (NIR) fluorescent probes have played vital roles in biological application due to their low interference from background fluorescence, deep tissue penetration, high sensitivity, and minimal photodamage to biological samples. They are widely utilized in molecular recognition, medical diagnosis, biomolecular detection, and biological imaging. Herein, we provide a review of recent advancements in cyanine-based NIR fluorescent probes for the detection of pH, cells, tumor as well as their application in photothermal therapy (PTT) and photodynamic therapy (PDT).

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来源期刊

ChemBioChem 生物-生化与分子生物学

CiteScore

6.10

自引率

3.10%

发文量

407

审稿时长

1 months

期刊介绍： ChemBioChem (Impact Factor 2018: 2.641) publishes important breakthroughs across all areas at the interface of chemistry and biology, including the fields of chemical biology, bioorganic chemistry, bioinorganic chemistry, synthetic biology, biocatalysis, bionanotechnology, and biomaterials. It is published on behalf of Chemistry Europe, an association of 16 European chemical societies, and supported by the Asian Chemical Editorial Society (ACES).