三种常用单细胞 RNA 测序方案的丢失率比较

IF 16.4 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Accounts of Chemical Research Pub Date : 2024-07-20 DOI:10.1080/13102818.2024.2379837

Omar Alaqeeli

引用次数: 0

摘要

基因缺失是 RNA 测序过程中不可避免的现象，有时会被误认为是基因不活跃。在这里，我们比较了 SMARTer、Smart-Seq 和 Tang 这三种测序方案在基因缺失方面的表现。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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A comparison of dropout rate of three commonly used single cell RNA-sequencing protocols

Dropout is an inevitable event in the RNA sequencing process and it is sometimes mistaken with gene inactivity. Here we compare three sequencing protocols, SMARTer, Smart-Seq and Tang, in terms of ...

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来源期刊

Accounts of Chemical Research 化学-化学综合

CiteScore

31.40

自引率

1.10%

发文量

312

审稿时长

2 months

期刊介绍： Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.