用于生物医学植入设备的功能性有机聚合物涂层的最新进展

IF 6.3 1区 工程技术 Q1 ENGINEERING, MECHANICAL
Friction Pub Date : 2024-07-22 DOI:10.1007/s40544-023-0850-7
Yinuo Yang, Yiran Jia, Yanran Zhao, Haimang Wang, Hongyu Zhang
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引用次数: 0

摘要

有机聚合物涂层在生物医学领域得到了普遍应用,在实现生物防污、药物输送和抑菌等方面发挥着重要作用。随着高分子科学的不断发展,有机聚合物涂层可以设计出复杂而先进的功能,有利于构建具有不同性能的生物医学材料。根据材料的不同物理和化学性质,生物医学有机聚合物涂层材料可分为齐聚物聚合物、非离子聚合物和生物大分子。涂层与基底的结合策略包括物理吸附、化学接枝和自粘。虽然涂层材料和施工方法各不相同,但许多生物医学聚合物涂层已被开发出来,以实现优异的性能,如增强润滑、消炎、防污、抗菌、药物释放、防锈、抗血栓等。因此,大量生物医学聚合物涂层已被用于人工肺、输尿管支架、血管分流器和人工关节。在这篇综述中,我们总结了生物医学有机聚合物涂层的不同类型、性质、构造方法、生物功能和临床应用,并展望了有机聚合物涂层在生物医学领域的未来发展方向。希望本综述对设计和合成具有各种生物医学用途的功能性有机聚合物涂层有所帮助。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Recent developments in functional organic polymer coatings for biomedical applications in implanted devices

Recent developments in functional organic polymer coatings for biomedical applications in implanted devices

Organic polymer coatings have been commonly used in biomedical field, which play an important role in achieving biological antifouling, drug delivery, and bacteriostasis. With the continuous development of polymer science, organic polymer coatings can be designed with complex and advanced functions, which is conducive to the construction of biomedical materials with different performances. According to different physical and chemical properties of materials, biomedical organic polymer coating materials are classified into zwitterionic polymers, non-ionic polymers, and biomacromolecules. The strategies of combining coatings with substrates include physical adsorption, chemical grafting, and self-adhesion. Though the coating materials and construction methods are different, many biomedical polymer coatings have been developed to achieve excellent performances, i.e., enhanced lubrication, anti-inflammation, antifouling, antibacterial, drug release, anti-encrustation, anti-thrombosis, etc. Consequently, a large number of biomedical polymer coatings have been used in artificial lungs, ureteral stent, vascular flow diverter, and artificial joints. In this review, we summarize different types, properties, construction methods, biological functions, and clinical applications of biomedical organic polymer coatings, and prospect future direction for development of organic polymer coatings in biomedical field. It is anticipated that this review can be useful for the design and synthesis of functional organic polymer coatings with various biomedical purposes.

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来源期刊
Friction
Friction Engineering-Mechanical Engineering
CiteScore
12.90
自引率
13.20%
发文量
324
审稿时长
13 weeks
期刊介绍: Friction is a peer-reviewed international journal for the publication of theoretical and experimental research works related to the friction, lubrication and wear. Original, high quality research papers and review articles on all aspects of tribology are welcome, including, but are not limited to, a variety of topics, such as: Friction: Origin of friction, Friction theories, New phenomena of friction, Nano-friction, Ultra-low friction, Molecular friction, Ultra-high friction, Friction at high speed, Friction at high temperature or low temperature, Friction at solid/liquid interfaces, Bio-friction, Adhesion, etc. Lubrication: Superlubricity, Green lubricants, Nano-lubrication, Boundary lubrication, Thin film lubrication, Elastohydrodynamic lubrication, Mixed lubrication, New lubricants, New additives, Gas lubrication, Solid lubrication, etc. Wear: Wear materials, Wear mechanism, Wear models, Wear in severe conditions, Wear measurement, Wear monitoring, etc. Surface Engineering: Surface texturing, Molecular films, Surface coatings, Surface modification, Bionic surfaces, etc. Basic Sciences: Tribology system, Principles of tribology, Thermodynamics of tribo-systems, Micro-fluidics, Thermal stability of tribo-systems, etc. Friction is an open access journal. It is published quarterly by Tsinghua University Press and Springer, and sponsored by the State Key Laboratory of Tribology (TsinghuaUniversity) and the Tribology Institute of Chinese Mechanical Engineering Society.
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