乳腺放射治疗后的闭塞性支气管炎组织化肺炎（BOOP）。

IF 3.4 3区医学 Q2 ONCOLOGY

Practical Radiation Oncology Pub Date : 2024-11-01 DOI:10.1016/j.prro.2024.06.008

Mara Caroprese MD , Laura Cella MD , Angela Barillaro MD , Caterina Oliviero MD , Stefania Clemente MD , Pierpaolo Mainenti MD , Roberto Pacelli MD , Manuel Conson MD

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引用次数: 0

摘要

本文报告了一例 77 岁类风湿性关节炎（RA）女性患者的病例，该患者因左乳腺癌接受了保乳手术，随后接受了放射治疗（RT），并在 RT 术后和接种 COVID-19 疫苗期间患上了阻塞性支气管炎组织化肺炎（BOOP）。BOOP的发病率在乳腺RT术后并不常见（1.2%-2.9%），但特定的易感因素可能起作用。在该患者中，RA 和疫苗可能会引发炎症级联反应，从而增加她患组织性肺炎的风险。我们的报告强调了影响辐射诱发的不常见疾病（如特定亚组患者的 BOOP）发生的因素的重要性。有必要开展进一步研究，以评估增加辐射敏感性的因素。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Bronchiolitis Obliterans Organizing Pneumonia After Breast Radiation Therapy

Presented here is a case report of a 77-year-old woman affected by rheumatoid arthritis who underwent breast-conserving surgery followed by radiation therapy (RT) for left-breast cancer and developed bronchiolitis obliterans organizing pneumonia (BOOP) after RT and during a COVID-19 vaccination campaign. BOOP incidence is an uncommon morbidity after breast RT (1.2%-2.9%); however, specific predisposing factors can play a role. In this patient, both rheumatoid arthritis and the vaccine may have predisposed her to an increased risk of organizing pneumonia, probably by triggering a proinflammatory cascade. Our report highlights the importance of factors that influence the occurrence of uncommon radiation-induced morbidities, such as BOOP, in specific subsets of patients. Further studies are necessary to evaluate factors increasing radiation sensitivity.

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来源期刊

Practical Radiation Oncology Medicine-Radiology, Nuclear Medicine and Imaging

CiteScore

5.20

自引率

6.10%

发文量

177

审稿时长

34 days

期刊介绍： The overarching mission of Practical Radiation Oncology is to improve the quality of radiation oncology practice. PRO''s purpose is to document the state of current practice, providing background for those in training and continuing education for practitioners, through discussion and illustration of new techniques, evaluation of current practices, and publication of case reports. PRO strives to provide its readers content that emphasizes knowledge "with a purpose." The content of PRO includes: Original articles focusing on patient safety, quality measurement, or quality improvement initiatives Original articles focusing on imaging, contouring, target delineation, simulation, treatment planning, immobilization, organ motion, and other practical issues ASTRO guidelines, position papers, and consensus statements Essays that highlight enriching personal experiences in caring for cancer patients and their families.