双冲洗 HEDP 与含专利添加剂的次氯酸钠溶液的兼容性。

IF 3.5 2区医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE

Journal of endodontics Pub Date : 2024-10-01 DOI:10.1016/j.joen.2024.07.007

Honey Kottathil MDent , Matthias Zehnder PhD , Andrea Gubler , Thomas Attin PhD , Rajkumar Narkedamalli MDS , Nidambur Vasudev Ballal MDS, PhD

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引用次数: 0

摘要

简介1-hydroxyethylidene-1,1-diphosphonic acid（1-羟基亚乙基-1,1-二膦酸）的一种盐已于几年前商品化。已对这种所谓的双冲洗 HEDP 的综合作用以及与纯 NaOCl 溶液的相互作用进行了测试。本研究的目的是评估双冲洗剂与含有专利添加剂的 NaOCl 溶液之间的相互作用：对指定的牙髓NaOCl溶液进行了测试，这些溶液有两种不同的浓度（2% 和 5.25%），分别不含或含添加剂（Chloraxid 和 Chloraxid Extra）。在溶液中存在或不存在 HEDP（9%）的情况下，对它们的一些关键化学和物理特性进行了测定。此外，还在拔出的牙齿（每组 10 颗，共 90 颗牙齿）中评估了测试溶液和对照溶液的软组织溶解功效：结果：2% Chloraxid 溶液中的 NaOCl 含量略高于标示浓度，而 5.25% 溶液中的 NaOCl 含量低于标示浓度。特级氯消毒剂溶液中的添加剂既不会改变其表面张力，也不会改变其粘度。在任何一种测试过的 NaOCl 溶液中加入 HEDP 都会降低其 pH 值，增加其表面张力和粘度。所有 NaOCl 溶液在第一小时内由 HEDP 引起的可用氯损失相似。根管中软组织的溶解受 NaOCl 浓度的影响，但既不受 Chloraxid 溶液中任何 NaOCl 专有添加剂的影响，也不受添加 Dual Rinse HEDP 的影响：结论：专有添加剂对任何测试参数都没有影响，包括 "额外 "溶液的表面张力。NaOCl/HEDP 混合溶液的粘度增加值得进一步关注。

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Compatibility of Dual Rinse 1-Hydroxyethane-1,1-Diphosphonic Acid with Sodium Hypochlorite Solutions Containing Proprietary Additives

Introduction

A salt of 1-hydroxyethylidene-1,1-diphosphonic acid (HEDP) was commercialized some years ago. This so-called Dual Rinse (DR) HEDP has been tested for its combined actions and interactions with pure sodium hypochlorite (NaOCl) solutions. The aim of this study was to assess DR interactions with NaOCl solutions containing proprietary additives.

Methods

Designated endodontic NaOCl solutions that come at 2 different strengths (2% and 5.25%), and without or with additives (Chloraxid and Chloraxid Extra, respectively) were tested. Some of their key chemical and physical properties were determined in the presence or absence of HEDP (9%) in the solution. In addition, soft tissue dissolution efficacy of test and control solutions was assessed in extracted teeth (n = 10 per group, 90 teeth in total).

Results

The NaOCl content in the 2% Chloraxid solutions was slightly above, that in the 5.25% solutions below the labeled concentration. The additives in the Chloraxid Extra solutions neither altered their surface tension nor their viscosity. The addition of HEDP to any of the tested NaOCl solutions reduced their pH, and increased their surface tension and viscosity. HEDP-induced available chlorine loss over the first hour was similar between all NaOCl solutions. Soft tissue dissolution in the root canals was affected by NaOCl concentration, but neither by any proprietary NaOCl additive in the Chloraxid solutions, nor the addition of DR HEDP.

Conclusions

Proprietary additives had no influence on any of the tested parameters, including surface tension of the "Extra" solutions. The increased viscosity of combined NaOCl/HEDP solutions deserves further attention.

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来源期刊

Journal of endodontics 医学-牙科与口腔外科

CiteScore

8.80

自引率

9.50%

发文量

224

审稿时长

42 days

期刊介绍： The Journal of Endodontics, the official journal of the American Association of Endodontists, publishes scientific articles, case reports and comparison studies evaluating materials and methods of pulp conservation and endodontic treatment. Endodontists and general dentists can learn about new concepts in root canal treatment and the latest advances in techniques and instrumentation in the one journal that helps them keep pace with rapid changes in this field.