反刍是否会减缓注意力偏差修正对抑郁症状的影响？

Q3 Psychology

Journal of Affective Disorders Reports Pub Date : 2024-07-01 DOI:10.1016/j.jadr.2024.100824

Hallvard Solbø Hagen , Jan Ivar Røssberg , Catherine J. Harmer , Rune Jonassen , Nils Inge Landrø , Ragnhild Bø

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引用次数: 0

摘要

背景目前对重度抑郁障碍的治疗仍使许多患者的病情略有改善。注意力偏差修正（ABM）是一种可作为亚组患者辅助治疗的方法。我们研究了经常被发现与消极注意偏差有关的反刍是否会在复发性抑郁症患者的计算机化 ABM 程序中起到调节变量的作用。结果在干预后或随访 1 个月时，ABM 和 RRS-B 对 HDRS 或 BDI-II 没有显著的交互作用。此外，训练前的注意力偏差与 RRS-B 没有相关性：结论在迄今为止最大规模的 ABM 临床研究中，沉思反刍对临床抑郁量表没有调节作用。

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Does rumination moderate the effect of attention bias modification for depressive symptoms?

Background

Current treatment of major depressive disorders still leave many patients with modest improvement. Attention Bias Modification (ABM) is an approach that may serve as an adjuvant therapy for subgroups of patients. We examined whether rumination, often found to be associated with a negative attentional bias, acts as a moderating variable in a computerized ABM procedure in participants with recurrent depression.

Methods

A total of 301 patients were randomized to receive either active - or sham ABM twice daily for 14 days. A regression-based moderator analysis was applied to evaluate whether baseline brooding, from the Rumination Response Scale (RRS-B), moderated the effect of ABM on Hamilton Depression Rating Scale (HDRS) and Beck Depression Inventory II (BDI-II).

Results

There was no significant interaction effect of ABM and RRS-B on HDRS or BDI-II at post-intervention or at 1 month follow-up. In addition, no correlation was found for pre-training attention bias and RRS-B.