Luis B Godínez-Córdova, Héctor González-Pacheco, Guering Eid-Lidt, Daniel Manzur-Sandoval, Rodrigo Gopar-Nieto, Daniel Sierra-Lara-Martínez, José L Briseño-de la Cruz, Diego Araiza-Garaygordobil, Salvador Mendoza-García, Alfredo Altamirano-Castillo, Alexandra Arias-Mendoza
{"title":"在一个中等收入国家的大学中心接受经皮冠状动脉介入治疗的患者中，无回流现象的发生率和对预后的影响。","authors":"Luis B Godínez-Córdova, Héctor González-Pacheco, Guering Eid-Lidt, Daniel Manzur-Sandoval, Rodrigo Gopar-Nieto, Daniel Sierra-Lara-Martínez, José L Briseño-de la Cruz, Diego Araiza-Garaygordobil, Salvador Mendoza-García, Alfredo Altamirano-Castillo, Alexandra Arias-Mendoza","doi":"10.24875/ACM.23000120","DOIUrl":null,"url":null,"abstract":"<p><strong>Objective: </strong>To analyze the prevalence of no-reflow and the 30-day mortality in a university center in a middle-income country.</p><p><strong>Method: </strong>We analyzed 2463 patients who underwent primary PCI from January 2006 to December 2021. The outcome measure was 30-day mortality.</p><p><strong>Results: </strong>Of a total of 2463 patients, no-reflow phenomenon was found in 413 (16.8%) patients, 30-day mortality was 16.7 vs. 4.29% (p < 0.001). Patients with no-reflow were older 60 (53-69.5) vs. 59 (51-66) (p = 0.001), with a higher delay in onset of symptom to emergency department arrival 270 vs. 247 min (p = 0.001). No-reflow patients also had had fewer previous myocardial infarction, 11.6 vs. 18.4 (p = 0.001) and a Killip class > 1, 37 vs. 26% (p < 0.001). No-reflow patients were more likely to have an anterior myocardial infarction (55.4 vs. 47.8%; p = 0.005) and initial TIMI flow 0 (76 vs. 68%; p < 0.001).</p><p><strong>Conclusion: </strong>No-reflow occurred in 16.8% of STEMI patients undergoing primary PCI and was more likely with older age, delayed presentation, anterior myocardial infarction and Killip class > 1. No-reflow was associated with a higher mortality at 30-day follow-up.</p>","PeriodicalId":93885,"journal":{"name":"Archivos de cardiologia de Mexico","volume":"94 3","pages":"331-340"},"PeriodicalIF":0.0000,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11259416/pdf/","citationCount":"0","resultStr":"{\"title\":\"Prevalence and prognostic implications of the no-reflux phenomenon in patients undergoing primary percutaneous coronary intervention at a university center in a middle-income country.\",\"authors\":\"Luis B Godínez-Córdova, Héctor González-Pacheco, Guering Eid-Lidt, Daniel Manzur-Sandoval, Rodrigo Gopar-Nieto, Daniel Sierra-Lara-Martínez, José L Briseño-de la Cruz, Diego Araiza-Garaygordobil, Salvador Mendoza-García, Alfredo Altamirano-Castillo, Alexandra Arias-Mendoza\",\"doi\":\"10.24875/ACM.23000120\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Objective: </strong>To analyze the prevalence of no-reflow and the 30-day mortality in a university center in a middle-income country.</p><p><strong>Method: </strong>We analyzed 2463 patients who underwent primary PCI from January 2006 to December 2021. The outcome measure was 30-day mortality.</p><p><strong>Results: </strong>Of a total of 2463 patients, no-reflow phenomenon was found in 413 (16.8%) patients, 30-day mortality was 16.7 vs. 4.29% (p < 0.001). Patients with no-reflow were older 60 (53-69.5) vs. 59 (51-66) (p = 0.001), with a higher delay in onset of symptom to emergency department arrival 270 vs. 247 min (p = 0.001). No-reflow patients also had had fewer previous myocardial infarction, 11.6 vs. 18.4 (p = 0.001) and a Killip class > 1, 37 vs. 26% (p < 0.001). No-reflow patients were more likely to have an anterior myocardial infarction (55.4 vs. 47.8%; p = 0.005) and initial TIMI flow 0 (76 vs. 68%; p < 0.001).</p><p><strong>Conclusion: </strong>No-reflow occurred in 16.8% of STEMI patients undergoing primary PCI and was more likely with older age, delayed presentation, anterior myocardial infarction and Killip class > 1. No-reflow was associated with a higher mortality at 30-day follow-up.</p>\",\"PeriodicalId\":93885,\"journal\":{\"name\":\"Archivos de cardiologia de Mexico\",\"volume\":\"94 3\",\"pages\":\"331-340\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2024-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11259416/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Archivos de cardiologia de Mexico\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.24875/ACM.23000120\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Archivos de cardiologia de Mexico","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.24875/ACM.23000120","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Prevalence and prognostic implications of the no-reflux phenomenon in patients undergoing primary percutaneous coronary intervention at a university center in a middle-income country.
Objective: To analyze the prevalence of no-reflow and the 30-day mortality in a university center in a middle-income country.
Method: We analyzed 2463 patients who underwent primary PCI from January 2006 to December 2021. The outcome measure was 30-day mortality.
Results: Of a total of 2463 patients, no-reflow phenomenon was found in 413 (16.8%) patients, 30-day mortality was 16.7 vs. 4.29% (p < 0.001). Patients with no-reflow were older 60 (53-69.5) vs. 59 (51-66) (p = 0.001), with a higher delay in onset of symptom to emergency department arrival 270 vs. 247 min (p = 0.001). No-reflow patients also had had fewer previous myocardial infarction, 11.6 vs. 18.4 (p = 0.001) and a Killip class > 1, 37 vs. 26% (p < 0.001). No-reflow patients were more likely to have an anterior myocardial infarction (55.4 vs. 47.8%; p = 0.005) and initial TIMI flow 0 (76 vs. 68%; p < 0.001).
Conclusion: No-reflow occurred in 16.8% of STEMI patients undergoing primary PCI and was more likely with older age, delayed presentation, anterior myocardial infarction and Killip class > 1. No-reflow was associated with a higher mortality at 30-day follow-up.
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