我们是否应该对小肠腺癌切除术后的患者定期进行胶囊内镜监测?病例报告与讨论。

IF 16.4 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY
Accounts of Chemical Research Pub Date : 2024-10-01 Epub Date: 2024-07-19 DOI:10.1055/a-2360-8586
Damian Wiedbrauck, Stephan Hollerbach, Felix Wiedbrauck
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引用次数: 0

摘要

由于小肠肿瘤非常罕见,有关视频胶囊内窥镜(VCE)在检测小肠肿瘤方面的作用的前瞻性数据非常有限。目前的指南并不主张对小肠肿瘤切除术后的患者进行监测性 VCE,这主要是由于缺乏数据。在此,我们报告了一名 81 岁的男性患者,他在 15 年前接受了回肠段腺癌根治性切除术,7 年前又接受了空肠段腺癌切除术(TNM 分类:pT2 pN0 (0/2) G2M0)。现在,他出现了黑便、进行性呼吸困难和血红蛋白水平下降。VCE显示,之前切除的空肠腺癌在肠道局部复发,导致第二次空肠分段切除术(TNM分类:pT3 L1 pN0 (0/5) G2 M0)。我们认为,在该患者第一次空肠腺癌切除术后定期进行监测性 VCE 可能有助于更早地发现肿瘤复发。因此,我们建议至少在复发性小肠恶性肿瘤患者中考虑定期监测 VCE。不过,今后还需要进行前瞻性研究来验证我们的发现。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Should we perform regular surveillance capsule endoscopies in patients following small-bowel adenocarcinoma resection? A case report and discussion.

Because small-bowel tumors are rare, prospective data on the utility of video capsule endoscopy (VCE) for their detection are limited. Current guidelines do not advocate for surveillance VCEs in patients following small-bowel tumor resection, which is mostly due to a lack of data. Here, we report an 81-year-old male patient who had undergone curative segmental ileal adenocarcinoma resection 15 years ago and another segmental jejunal adenocarcinoma resection (TNM-Classification: pT2 pN0 (0/2) G2M0) 7 years ago. He now presents with melena, progressive dyspnea, and decreased hemoglobin levels. VCE revealed local intestinal recurrence of the previously resected jejunal adenocarcinoma, leading to a second segmental jejunal resection (TNM-Classification: pT3 L1 pN0 (0/5) G2 M0). We believe that regular surveillance VCEs after the first jejunal adenocarcinoma resection might have facilitated earlier detection of tumor recurrence in this patient's case. Therefore, we suggest considering regular surveillance VCEs, at least in patients with recurrent small-bowel malignancies. However, future prospective studies are warranted to validate our findings.

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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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