上皮细胞性单形性肠 T 细胞淋巴瘤:病例报告和文献综述

IF 0.2 Q4 ONCOLOGY
Joseph Alburqueque-Melgarejo , Brady Beltrán Gárate , Jhony A. De la Cruz-Vargas
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引用次数: 0

摘要

单形上皮细胞性肠T细胞淋巴瘤(MEITL)是一种罕见的胃肠道T细胞淋巴瘤,病程凶险。以前,这种淋巴瘤被命名为伴有肠病的 II 型 T 细胞淋巴瘤。但后来由于其特殊性,被归类为另一种类型。这种肿瘤通常累及空肠和回肠,临床表现通常为肠穿孔、肠梗阻或出血。其诊断需要进行组织病理学评估,并与影响肠道的其他类型 T 细胞淋巴瘤进行鉴别。这种淋巴瘤的预后通常很差,治疗方法也很有限,主要是进行诱导化疗,然后进行自体骨髓移植。本文介绍了秘鲁首例 MEITL 病例,患者是一名老年患者,因肠穿孔急诊入院,肿瘤多次复发。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Epitheliotropic monomorphic intestinal T cell lymphoma: Case report and literature review

Monomorphic epitheliotropic intestinal T-cell lymphoma (MEITL) is a rare type of T-cell lymphoma of the gastrointestinal tract that presents an aggressive course. Previously, this entity was named type II T-cell lymphoma associated with enteropathy. However, in later years it was classified as a different entity due to its particular characteristics. This neoplasm usually affects the jejunum and ileum and usually has a clinical presentation with intestinal perforation, intestinal obstruction or bleeding. Its diagnosis requires histopathological evaluation and differentiation from other types of T cell lymphomas that affect the intestine. Its prognosis is usually very poor and therapeutic options are limited and are based on induction chemotherapy followed by autologous bone marrow transplant. This article presents the first case of MEITL in Peru, in an elderly patient who presented at hospital emergency with intestinal perforation and that presented multiple relapses of the neoplasm.

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