Influence of the presence of different signatures on the heat transfer profile of laminar flow inside a microchannel.

Despite the fact that the process of transferring heat and mass involves a high-pressure decline, microchannels are utilized in research involving extremely efficient heat and mass transfer processes, such as in the systems of the lungs and kidneys. Due to their high surface-to-volume ratio and compact volume, microchannels have demonstrated superior thermal performance. Microchannel flows have been shown to be a high-performance cooling method that dissipates heat flux from tiny localized hot spots over a large surface area. Due to the bidirectional nature of signalling at cell adhesions, it is necessary to examine mechanotransduction in microenvironments that are physiologically pertinent. The need to enable the study of mechanotransduction in environments with physiologically relevant mechanical properties and architecture had prompted the development of microfluidic platforms that improve standard in vitro cell culture. This article emphasizes the modulation of temperature and velocity variations within the working fluid by emphasizing the thermo-fluid coupling effects in micro-channels. In the case of two input boundary conditions, the effect of heat distributions on fluid flow with respect to micro-fins within a microchannel was investigated numerically. After comparing the results for both boundary conditions, it was found that rectangular fins had the highest heat transfer to the fluid flow, while semi-elliptical fins had the lowest heat transf