在 COVID-19 大流行期间治疗渗出性老年性黄斑变性患者的长期疗效

Q3 Medicine

Archivos De La Sociedad Espanola De Oftalmologia Pub Date : 2024-11-01 DOI:10.1016/j.oftal.2024.06.001

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引用次数: 0

摘要

目的对我国 nAMD 患者进行 COVID-19 封闭治疗对视觉效果和新生血管病变活动性的长期影响（24 个月）进行量化研究。结果纳入了 144 名 nAMD 患者（168 只眼），其中 51 名（35.42%）是在禁闭期间就诊的，24 个月时最终纳入的患者总数为 118 名（133 只眼）。在 12 个月和 24 个月的随访中，之前的视力值为 57.99 ± 23.68 个字母，平均下降了 6.87 个字母（±16.84）和 7.89 个字母（±19.58），具有临床相关性和统计学意义。与大流行前的国家数据库相比，本组患者在 12 个月时的注射和就诊次数中位数较低，在 24 个月时趋于相等。我们比较了在禁闭期间或治疗间隔超过 8 周（Tq8w）时就诊的患者，没有发现视力方面的差异。结论nAMD 患者的视力在禁闭后显著下降，这可能是由于第一年的抗血管生成注射和就诊次数较少，尽管第二年的注射和就诊次数增加，接近禁闭前报告的次数，但视力并未恢复。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文本刊更多论文

Resultados a largo plazo del tratamiento de los pacientes con degeneración macular asociada a la edad exudativa durante la pandemia por COVID-19

Purpose

To quantify the long-term impact (24 months) on the visual results and activity of neovascular lesions of COVID-19 confinement in patients with nAMD in our population.

Methods

A retrospective observational study of patients with nAMD who attended consultation or were treated during the 3 months before confinement was carried out.

Results

144 patients (168 eyes) with nAMD were included, 51 of them (35.42%) came during confinement, and at 24 months the final cohort was 118 patients (133 eyes).

The previous VA of 57.99 ± 23.68 letters decreased, clinically relevant and statistically significant, by an average of 6.87 (±16.84) and 7.89 (±19.58) at 12- and 24-months follow-up. This change differs significantly from the two-year vision change observed in the national database of pretreated patients.

The median number of injections and consultations is lower in our group at 12 months, compared to the pre-pandemic national database, and tends to equalize at 24 months.

We did not find differences in vision when we compared patients who attended consultations during confinement or in treatment intervals greater than 8 weeks (Tq8w).

Conclusions

The VA of patients with nAMD decreased significantly after confinement, probably due to the lower number of antiangiogenic injections and consultations during the first year, and did not recover during the second year despite the increase in the number of injections and visits close to those reported before confinement_.

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来源期刊

Archivos De La Sociedad Espanola De Oftalmologia Medicine-Ophthalmology

CiteScore

1.20

自引率

0.00%

发文量

109

审稿时长

78 days

期刊介绍： La revista Archivos de la Sociedad Española de Oftalmología, editada mensualmente por la propia Sociedad, tiene como objetivo publicar trabajos de investigación básica y clínica como artículos originales; casos clínicos, innovaciones técnicas y correlaciones clinicopatológicas en forma de comunicaciones cortas; editoriales; revisiones; cartas al editor; comentarios de libros; información de eventos; noticias personales y anuncios comerciales, así como trabajos de temas históricos y motivos inconográficos relacionados con la Oftalmología. El título abreviado es Arch Soc Esp Oftalmol, y debe ser utilizado en bibliografías, notas a pie de página y referencias bibliográficas.