{"title":"探索消化道肿瘤中肿瘤干细胞的治疗策略","authors":"Xinliu Xu","doi":"10.32629/jcmr.v5i2.2334","DOIUrl":null,"url":null,"abstract":"To explore the potential and challenges of tumour stem cells in the treatment of digestive tract tumours, the article analyses the key role of tumour stem cells in tumourigenesis and treatment resistance using a systematic review as an approach. Tumour stem cells are capable of self-renewal and multidirectional differentiation, which have a significant impact on long-term tumour survival and recurrence. Therapeutic strategies for targeting tumour stem cells include labelling and isolation techniques as well as the development of targeted drugs aimed at improving therapeutic efficacy and prolonging patient survival. However, therapeutic resistance caused by tumour stem cells remains one of the challenges and requires further in-depth studies and effective therapeutic strategies, providing theoretical support for future clinical studies and the development of individualized treatment protocols.","PeriodicalId":15431,"journal":{"name":"Journal of Clinical Medicine Research","volume":" 17","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2024-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Exploring Therapeutic Strategies for Tumour Stem Cells in Digestive Tract Tumours\",\"authors\":\"Xinliu Xu\",\"doi\":\"10.32629/jcmr.v5i2.2334\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"To explore the potential and challenges of tumour stem cells in the treatment of digestive tract tumours, the article analyses the key role of tumour stem cells in tumourigenesis and treatment resistance using a systematic review as an approach. Tumour stem cells are capable of self-renewal and multidirectional differentiation, which have a significant impact on long-term tumour survival and recurrence. Therapeutic strategies for targeting tumour stem cells include labelling and isolation techniques as well as the development of targeted drugs aimed at improving therapeutic efficacy and prolonging patient survival. However, therapeutic resistance caused by tumour stem cells remains one of the challenges and requires further in-depth studies and effective therapeutic strategies, providing theoretical support for future clinical studies and the development of individualized treatment protocols.\",\"PeriodicalId\":15431,\"journal\":{\"name\":\"Journal of Clinical Medicine Research\",\"volume\":\" 17\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2024-07-05\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Clinical Medicine Research\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.32629/jcmr.v5i2.2334\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Clinical Medicine Research","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.32629/jcmr.v5i2.2334","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Exploring Therapeutic Strategies for Tumour Stem Cells in Digestive Tract Tumours
To explore the potential and challenges of tumour stem cells in the treatment of digestive tract tumours, the article analyses the key role of tumour stem cells in tumourigenesis and treatment resistance using a systematic review as an approach. Tumour stem cells are capable of self-renewal and multidirectional differentiation, which have a significant impact on long-term tumour survival and recurrence. Therapeutic strategies for targeting tumour stem cells include labelling and isolation techniques as well as the development of targeted drugs aimed at improving therapeutic efficacy and prolonging patient survival. However, therapeutic resistance caused by tumour stem cells remains one of the challenges and requires further in-depth studies and effective therapeutic strategies, providing theoretical support for future clinical studies and the development of individualized treatment protocols.