阿尔茨海默氏症治疗中的纳米医学:增强给药策略

Q3 Medicine
Archna Singh, Avijit Mazumder, Saumya Das, Rashmi Mishra, M. Chaitanya
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引用次数: 0

摘要

阿尔茨海默病(AD)是一种渐进性神经退行性疾病,由大脑错综复杂的神经网络中的β-淀粉样蛋白斑块堆积引起。治疗阿尔茨海默病的持久疗法仍然遥遥无期,因为目前的药物方案只能提供延缓其发展的潜力。然而,纳米技术已经在医疗干预领域证明了它的功效。纳米技术在治疗阿尔茨海默病方面大有可为,尤其是在疾病检测和提供替代治疗方法方面。纳米技术在医疗应用方面的优越性已得到证实,因此在解决阿尔茨海默病的复杂问题、提供更好的诊断方法和新的治疗策略方面,纳米技术已成为一种具有巨大潜力的有力工具。然而,彻底研究和探索当前的局限性至关重要,目的是在增强药物吸收的同时最大限度地减少不良副作用和潜在毒性,从而优化整体治疗效果。利用纳米技术治疗阿尔茨海默病的前沿突破包括干细胞再生、纳米医学和神经保护等一系列显著进展。本研究深入探讨了纳米技术所取得的显著进步,特别研究了纳米技术在检测和治疗阿尔茨海默氏症等神经退行性疾病方面的关键作用,同时揭示了未来的挑战。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Nanomedicine in Alzheimer’s Therapy: Enhancing Drug Delivery Strategies
Alzheimer's disease (AD), a progressive neurodegenerative disorder, arises from the buildup of beta-amyloid plaques within the intricate neural networks of the brain. A lasting remedy for Alzheimer's disease remains elusive, as current pharmaceutical options merely offer the potential to decelerate its advancement. Nevertheless, nanotechnology has demonstrated its efficacy in the realm of medical interventions. Nanotechnology holds immense promise for the treatment of Alzheimer's disease, particularly in the realms of disease detection and providing alternative therapeutic approaches. With its demonstrated superiority in medical applications, nanotechnology emerges as a potent tool with significant potential in addressing the complexities of Alzheimer's disease, offering enhanced diagnostics and novel treatment strategies. This feat is achieved by augmenting the efficacy of drug administration through the penetration and surmounting of the BBB. Nonetheless, it is crucial to thoroughly investigate and explore the limitations at hand, aiming to minimize undesired side effects and potential toxicity while enhancing medication absorption, thereby optimizing the overall therapeutic outcome. Cutting-edge breakthroughs in Alzheimer's disease treatment utilizing nanotechnology encompass a spectrum of remarkable advancements, including stem cell regeneration, nanomedicine, and neuroprotection. The present investigation delves into the remarkable strides made in nanotechnology, specifically examining its pivotal role in detecting and treating neurodegenerative disorders such as Alzheimer's while shedding light on the challenges ahead.
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来源期刊
Current Nanomedicine
Current Nanomedicine Medicine-Medicine (miscellaneous)
CiteScore
2.00
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15
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