N. Ramirez, A. J. Zynda, C. Perry, C. Burley, S. Patel, H. Guercio, N. Bunker, J. French, A. Trbovich, M. Collins, A. Kontos
{"title":"A - 44 比较老年人脑震荡后的多领域临床评估结果","authors":"N. Ramirez, A. J. Zynda, C. Perry, C. Burley, S. Patel, H. Guercio, N. Bunker, J. French, A. Trbovich, M. Collins, A. Kontos","doi":"10.1093/arclin/acae052.44","DOIUrl":null,"url":null,"abstract":"\n \n \n To examine differences in demographics, medical history, injury characteristics, and multidomain clinical assessment outcomes between different age groups of older adults following concussion.\n \n \n \n This prospective study included participants aged 50+ years with a diagnosed concussion (<12 months) who presented to a specialty concussion clinic. Participants completed a clinical intake/interview (e.g., demographics) and a multidomain clinical assessment comprising symptoms (Clinical Profile Screen [CP-Screen]), cognitive (Repeatable Battery for the Assessment of Neuropsychological Status [RBANS]), psychological health (Patient Health Questionnaire-9 [PHQ-9], Generalized Anxiety Disoder-7 [GAD-7]), vestibular/ocular (Vestibular/Ocular Motor Screen [VOMS]), and quality of life (Neurological Quality of Life [Neuro-QoL]) at an initial visit. Older adults aged 50–59 and 60+ years were compared using independent samples t-tests, X2 tests, and analyses of covariance.\n \n \n \n 76 participants (M = 59.6¬ ± 6.3 years, 55.3% female) were included, 41 (53.9%) aged 50–59 and 35 (46.1%) aged 60+ years. The 50–59-year group had a greater proportion of females (68.3% vs. 40.0%, p = 0.01) and a history of anxiety (39.0% vs. 17.1%, p = 0.036). The 50–59-year group had worse Neuro-QoL (F[1, 72] = 5.1, p = 0.03, ηp2 = 0.10), RBANS recall (F[1, 72] = 7.1, p < 0.01, ηp2 = 0.09), RBANS fluency (F[1, 72] = 5.0, p = 0.03, ηp2 = 0.06), and RBANS list recognition (F[1, 72] = 4.1, p = 0.04, ηp2 = 0.06), controlling for sex and history of anxiety.\n \n \n \n This study demonstrated that adults aged 50–59 years were more likely to be female and have a history of anxiety compared to adults 60+ years. Interestingly, older adults 50–59 years demonstrated greater perceived difficulties in their cognitive abilities post-concussion, which was reflected in impairments on cognitive testing compared to adults 60+ years.\n","PeriodicalId":2,"journal":{"name":"ACS Applied Bio Materials","volume":" 23","pages":""},"PeriodicalIF":4.6000,"publicationDate":"2024-07-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"A - 44 A Comparison of Multi-Domain Clinical Assessment Outcomes in Older Adults Following Concussion\",\"authors\":\"N. Ramirez, A. J. Zynda, C. Perry, C. Burley, S. Patel, H. Guercio, N. Bunker, J. French, A. Trbovich, M. Collins, A. Kontos\",\"doi\":\"10.1093/arclin/acae052.44\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"\\n \\n \\n To examine differences in demographics, medical history, injury characteristics, and multidomain clinical assessment outcomes between different age groups of older adults following concussion.\\n \\n \\n \\n This prospective study included participants aged 50+ years with a diagnosed concussion (<12 months) who presented to a specialty concussion clinic. Participants completed a clinical intake/interview (e.g., demographics) and a multidomain clinical assessment comprising symptoms (Clinical Profile Screen [CP-Screen]), cognitive (Repeatable Battery for the Assessment of Neuropsychological Status [RBANS]), psychological health (Patient Health Questionnaire-9 [PHQ-9], Generalized Anxiety Disoder-7 [GAD-7]), vestibular/ocular (Vestibular/Ocular Motor Screen [VOMS]), and quality of life (Neurological Quality of Life [Neuro-QoL]) at an initial visit. Older adults aged 50–59 and 60+ years were compared using independent samples t-tests, X2 tests, and analyses of covariance.\\n \\n \\n \\n 76 participants (M = 59.6¬ ± 6.3 years, 55.3% female) were included, 41 (53.9%) aged 50–59 and 35 (46.1%) aged 60+ years. The 50–59-year group had a greater proportion of females (68.3% vs. 40.0%, p = 0.01) and a history of anxiety (39.0% vs. 17.1%, p = 0.036). The 50–59-year group had worse Neuro-QoL (F[1, 72] = 5.1, p = 0.03, ηp2 = 0.10), RBANS recall (F[1, 72] = 7.1, p < 0.01, ηp2 = 0.09), RBANS fluency (F[1, 72] = 5.0, p = 0.03, ηp2 = 0.06), and RBANS list recognition (F[1, 72] = 4.1, p = 0.04, ηp2 = 0.06), controlling for sex and history of anxiety.\\n \\n \\n \\n This study demonstrated that adults aged 50–59 years were more likely to be female and have a history of anxiety compared to adults 60+ years. 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A - 44 A Comparison of Multi-Domain Clinical Assessment Outcomes in Older Adults Following Concussion
To examine differences in demographics, medical history, injury characteristics, and multidomain clinical assessment outcomes between different age groups of older adults following concussion.
This prospective study included participants aged 50+ years with a diagnosed concussion (<12 months) who presented to a specialty concussion clinic. Participants completed a clinical intake/interview (e.g., demographics) and a multidomain clinical assessment comprising symptoms (Clinical Profile Screen [CP-Screen]), cognitive (Repeatable Battery for the Assessment of Neuropsychological Status [RBANS]), psychological health (Patient Health Questionnaire-9 [PHQ-9], Generalized Anxiety Disoder-7 [GAD-7]), vestibular/ocular (Vestibular/Ocular Motor Screen [VOMS]), and quality of life (Neurological Quality of Life [Neuro-QoL]) at an initial visit. Older adults aged 50–59 and 60+ years were compared using independent samples t-tests, X2 tests, and analyses of covariance.
76 participants (M = 59.6¬ ± 6.3 years, 55.3% female) were included, 41 (53.9%) aged 50–59 and 35 (46.1%) aged 60+ years. The 50–59-year group had a greater proportion of females (68.3% vs. 40.0%, p = 0.01) and a history of anxiety (39.0% vs. 17.1%, p = 0.036). The 50–59-year group had worse Neuro-QoL (F[1, 72] = 5.1, p = 0.03, ηp2 = 0.10), RBANS recall (F[1, 72] = 7.1, p < 0.01, ηp2 = 0.09), RBANS fluency (F[1, 72] = 5.0, p = 0.03, ηp2 = 0.06), and RBANS list recognition (F[1, 72] = 4.1, p = 0.04, ηp2 = 0.06), controlling for sex and history of anxiety.
This study demonstrated that adults aged 50–59 years were more likely to be female and have a history of anxiety compared to adults 60+ years. Interestingly, older adults 50–59 years demonstrated greater perceived difficulties in their cognitive abilities post-concussion, which was reflected in impairments on cognitive testing compared to adults 60+ years.
期刊介绍:
ACS Applied Bio Materials is an interdisciplinary journal publishing original research covering all aspects of biomaterials and biointerfaces including and beyond the traditional biosensing, biomedical and therapeutic applications.
The journal is devoted to reports of new and original experimental and theoretical research of an applied nature that integrates knowledge in the areas of materials, engineering, physics, bioscience, and chemistry into important bio applications. The journal is specifically interested in work that addresses the relationship between structure and function and assesses the stability and degradation of materials under relevant environmental and biological conditions.