{"title":"常见变异性免疫缺陷症--在资源有限的环境中被误诊的延迟诊断病例","authors":"S. Raina, Tanya Thakur, Korada Vivek Naidu, Bikram Shah, Manoj Thakur","doi":"10.18231/j.ijirm.2024.016","DOIUrl":null,"url":null,"abstract":"We report a case of common variable immunodeficiency (CVID) in a 42-year-old female who presented with history of recurrent rhinosinusitis for the last ten years. Patient had developed cough and progressive dyspnoea for last one year. Patient was admitted with community acquired pneumonia and sputum culture was positive for Pseudomonas aeruginosa. Common variable immunodeficiency was diagnosed ten years after the onset of symptoms. CVID is an underdiagnosed disorder because of the low index of suspicion, lack of awareness, poor facilities for the investigations and higher prevalence of infectious diseases in developing countries. CVID should be suspected in patients with recurrent rhinosinusitis or pneumonia and evaluation of serum immunoglobulins is advised.","PeriodicalId":14503,"journal":{"name":"IP Indian Journal of Immunology and Respiratory Medicine","volume":"44 8","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2024-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Common variable immunodeficiency- A delayed diagnosis of an underdiagnosed entity in resource limited setting\",\"authors\":\"S. Raina, Tanya Thakur, Korada Vivek Naidu, Bikram Shah, Manoj Thakur\",\"doi\":\"10.18231/j.ijirm.2024.016\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"We report a case of common variable immunodeficiency (CVID) in a 42-year-old female who presented with history of recurrent rhinosinusitis for the last ten years. Patient had developed cough and progressive dyspnoea for last one year. Patient was admitted with community acquired pneumonia and sputum culture was positive for Pseudomonas aeruginosa. Common variable immunodeficiency was diagnosed ten years after the onset of symptoms. CVID is an underdiagnosed disorder because of the low index of suspicion, lack of awareness, poor facilities for the investigations and higher prevalence of infectious diseases in developing countries. CVID should be suspected in patients with recurrent rhinosinusitis or pneumonia and evaluation of serum immunoglobulins is advised.\",\"PeriodicalId\":14503,\"journal\":{\"name\":\"IP Indian Journal of Immunology and Respiratory Medicine\",\"volume\":\"44 8\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2024-07-15\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"IP Indian Journal of Immunology and Respiratory Medicine\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.18231/j.ijirm.2024.016\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"IP Indian Journal of Immunology and Respiratory Medicine","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.18231/j.ijirm.2024.016","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Common variable immunodeficiency- A delayed diagnosis of an underdiagnosed entity in resource limited setting
We report a case of common variable immunodeficiency (CVID) in a 42-year-old female who presented with history of recurrent rhinosinusitis for the last ten years. Patient had developed cough and progressive dyspnoea for last one year. Patient was admitted with community acquired pneumonia and sputum culture was positive for Pseudomonas aeruginosa. Common variable immunodeficiency was diagnosed ten years after the onset of symptoms. CVID is an underdiagnosed disorder because of the low index of suspicion, lack of awareness, poor facilities for the investigations and higher prevalence of infectious diseases in developing countries. CVID should be suspected in patients with recurrent rhinosinusitis or pneumonia and evaluation of serum immunoglobulins is advised.