从僵硬的肿瘤中拯救 T 细胞
IF 6.6
1区 生物学
Q1 BIOCHEMISTRY & MOLECULAR BIOLOGY
引用次数: 0
摘要
在最近一期《细胞》（Cell）杂志上，Zhang 等人1 证明了实体瘤的机械特征可使 T 细胞功能失调，并确定了恢复这种 "衰竭 "状态的途径。本文章由计算机程序翻译，如有差异，请以英文原文为准。
Rescuing T cells from stiff tumors
In a recent issue of Cell, Zhang et al.1 demonstrate that mechanical features of a solid tumor can drive T cells into dysfunctionality and identify pathways that revert this “exhausted” state.
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来源期刊
Cell Chemical Biology
Biochemistry, Genetics and Molecular Biology-Molecular Medicine
CiteScore
14.70
自引率
2.30%
发文量
143
期刊介绍：
Cell Chemical Biology, a Cell Press journal established in 1994 as Chemistry & Biology, focuses on publishing crucial advances in chemical biology research with broad appeal to our diverse community, spanning basic scientists to clinicians. Pioneering investigations at the chemistry-biology interface, the journal fosters collaboration between these disciplines. We encourage submissions providing significant conceptual advancements of broad interest across chemical, biological, clinical, and related fields. Particularly sought are articles utilizing chemical tools to perturb, visualize, and measure biological systems, offering unique insights into molecular mechanisms, disease biology, and therapeutics.
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