医疗紧急情况下的舌下和口腔给药。

IF 2.6 4区 医学 Q1 MEDICINE, GENERAL & INTERNAL
Medicina Clinica Pub Date : 2024-12-27 Epub Date: 2024-07-14 DOI:10.1016/j.medcli.2024.05.008
Joan Ramon Roma, Pedro Castro Rebollo, Carla Bastida
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引用次数: 0

摘要

给药对于实现有效的药物治疗效果至关重要。在医疗紧急情况下,使用可替代传统给药途径(如口服或静脉注射途径)的药物尤其方便,但传统给药途径并不总是适合这些情况。因此,当需要快速起效时,舌下和口腔给药途径可替代传统途径。本综述的主要目的是总结在医疗紧急情况下使用舌下和口腔给药的证据。所获得的证据分为急诊科和重症监护室常见的四种情况:心血管急症、急性疼痛、躁动和癫痫状态。此外,还介绍了舌下和口腔给药途径的主要优缺点,以及克服这些途径局限性的未来给药前景。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Sublingual and buccal drug administration in medical emergencies].

Drug administration is crucial to achieve effective therapeutic drug outcomes. In medical emergencies, it is particularly convenient to use drugs that could be administered as an alternative to traditional routes (as oral or intravenous routes), that are not always suitable in these situations. Thus, sublingual and buccal routes offer an alternative to traditional routes, when a rapid onset of action is required. The main objective of this narrative review is to summarize the evidence for the use of sublingual and buccal drug administration in medical emergencies. The evidence obtained has been divided into four common scenarios found in the emergency department and intensive care units: cardiovascular emergencies, acute pain, agitation, and epileptic status. Moreover, the main advantages and disadvantages of sublingual and buccal routes are presented, as the future perspectives in the drug delivery field to overcome the limitations of these routes.

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来源期刊
Medicina Clinica
Medicina Clinica 医学-医学:内科
CiteScore
3.10
自引率
5.10%
发文量
295
审稿时长
22 days
期刊介绍: Medicina Clínica, fundada en 1943, es una publicación quincenal dedicada a la promoción de la investigación y de la práctica clínica entre los especialistas de la medicina interna, así como otras especialidades. Son características fundamentales de esta publicación el rigor científico y metodológico de sus artículos, la actualidad de los temas y, sobre todo, su sentido práctico, buscando siempre que la información sea de la mayor utilidad en la práctica clínica.
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