{"title":"疫苗接种政策的优化设计：纽芬兰和拉布拉多案例研究","authors":"Faraz Khoshbakhtian , Hamidreza Validi , Mario Ventresca , Dionne Aleman","doi":"10.1016/j.orl.2024.107140","DOIUrl":null,"url":null,"abstract":"<div><p>This paper proposes pandemic mitigation vaccination policies for Newfoundland and Labrador (NL) based on two compact mixed integer programming (MIP) models of the distance-based critical node detection problem (DCNDP). Our main focus is on two variants of the DCNDP that seek to minimize the number of connections with lengths of at most one (1-DCNDP) and two (2-DCNDP). A polyhedral study for the 1-DCNDP is conducted, and new aggregated inequalities are provided for the 2-DCNDP. The computational experiments show that the 2-DCNDP with aggregated inequalities outperforms the one with disaggregated inequalities for graphs with a density of at least 0.5%. We also study the strategic vaccine allocation problem as a real-world application of the DCNDP and conduct a set of computational experiments on a simulated contact network of NL. Our computational results demonstrate that the DCNDP-based strategies can have a better performance in comparison with the real-world strategies implemented during COVID-19.</p></div>","PeriodicalId":54682,"journal":{"name":"Operations Research Letters","volume":"55 ","pages":"Article 107140"},"PeriodicalIF":0.8000,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Optimal design of vaccination policies: A case study for Newfoundland and Labrador\",\"authors\":\"Faraz Khoshbakhtian , Hamidreza Validi , Mario Ventresca , Dionne Aleman\",\"doi\":\"10.1016/j.orl.2024.107140\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>This paper proposes pandemic mitigation vaccination policies for Newfoundland and Labrador (NL) based on two compact mixed integer programming (MIP) models of the distance-based critical node detection problem (DCNDP). Our main focus is on two variants of the DCNDP that seek to minimize the number of connections with lengths of at most one (1-DCNDP) and two (2-DCNDP). A polyhedral study for the 1-DCNDP is conducted, and new aggregated inequalities are provided for the 2-DCNDP. The computational experiments show that the 2-DCNDP with aggregated inequalities outperforms the one with disaggregated inequalities for graphs with a density of at least 0.5%. We also study the strategic vaccine allocation problem as a real-world application of the DCNDP and conduct a set of computational experiments on a simulated contact network of NL. Our computational results demonstrate that the DCNDP-based strategies can have a better performance in comparison with the real-world strategies implemented during COVID-19.</p></div>\",\"PeriodicalId\":54682,\"journal\":{\"name\":\"Operations Research Letters\",\"volume\":\"55 \",\"pages\":\"Article 107140\"},\"PeriodicalIF\":0.8000,\"publicationDate\":\"2024-07-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Operations Research Letters\",\"FirstCategoryId\":\"91\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0167637724000762\",\"RegionNum\":4,\"RegionCategory\":\"管理学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"OPERATIONS RESEARCH & MANAGEMENT SCIENCE\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Operations Research Letters","FirstCategoryId":"91","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0167637724000762","RegionNum":4,"RegionCategory":"管理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"OPERATIONS RESEARCH & MANAGEMENT SCIENCE","Score":null,"Total":0}
Optimal design of vaccination policies: A case study for Newfoundland and Labrador
This paper proposes pandemic mitigation vaccination policies for Newfoundland and Labrador (NL) based on two compact mixed integer programming (MIP) models of the distance-based critical node detection problem (DCNDP). Our main focus is on two variants of the DCNDP that seek to minimize the number of connections with lengths of at most one (1-DCNDP) and two (2-DCNDP). A polyhedral study for the 1-DCNDP is conducted, and new aggregated inequalities are provided for the 2-DCNDP. The computational experiments show that the 2-DCNDP with aggregated inequalities outperforms the one with disaggregated inequalities for graphs with a density of at least 0.5%. We also study the strategic vaccine allocation problem as a real-world application of the DCNDP and conduct a set of computational experiments on a simulated contact network of NL. Our computational results demonstrate that the DCNDP-based strategies can have a better performance in comparison with the real-world strategies implemented during COVID-19.
期刊介绍：
Operations Research Letters is committed to the rapid review and fast publication of short articles on all aspects of operations research and analytics. Apart from a limitation to eight journal pages, quality, originality, relevance and clarity are the only criteria for selecting the papers to be published. ORL covers the broad field of optimization, stochastic models and game theory. Specific areas of interest include networks, routing, location, queueing, scheduling, inventory, reliability, and financial engineering. We wish to explore interfaces with other fields such as life sciences and health care, artificial intelligence and machine learning, energy distribution, and computational social sciences and humanities. Our traditional strength is in methodology, including theory, modelling, algorithms and computational studies. We also welcome novel applications and concise literature reviews.
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