Zain Ali Nadeem, Umar Akram, Talha Bin Khalid, Muhammad Asfandyar Nadir, Muhammad Hasnat Akhtar
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Refractive Errors Linked to Autism Spectrum Disorders in the Pediatric Population and Young Adults: A Systematic Review and Meta-Analysis
While previous studies have demonstrated significant eye problems in children with autism spectrum disorders (ASDs), refractive errors have not been extensively studied in the context of ASDs. We systematically reviewed twenty-eight articles to assess whether refractive errors are linked with ASDs, and to determine the prevalence of refractive errors in children with ASDs. We found no significant association between ASDs and myopia or hyperopia, but a significantly increased risk of astigmatism was observed in children with ASDs. Pooled results of single-arm studies revealed a 14.1% prevalence of myopia, a 9.8% prevalence of hyperopia, and a 16.5% prevalence of astigmatism in children with ASDs. Future studies should incorporate a prospective design with age-matched comparison groups.
期刊介绍:
The Review Journal of Autism and Developmental Disorders publishes original articles that provide critical reviews of topics across the broad interdisciplinary research fields of autism spectrum disorders. Topics range from basic to applied and include but are not limited to genetics, neuroscience, diagnosis, applied behavior analysis, psychopharmacology, incidence, prevalence, etiology, differential diagnosis, treatment, measurement of treatment effects, education, perception and cognition. Topics across the life span are appropriate. In addition, given the high rates of comorbid conditions, the interface of sleep disorders, feeding problems, motor difficulties, ADHD, anxiety, depression and other disorders with autism spectrum disorders are appropriate. The Journal aims for an international audience as reflected in the editorial board.