{"title":"斯特林肽的逆选择全合成 839","authors":"Hiroshige Ogawa, Hugh Nakamura","doi":"10.1016/j.tchem.2024.100084","DOIUrl":null,"url":null,"abstract":"<div><p>The first total synthesis of the recently isolated strecintide 839 is reported. Strecintide 839 is one of the RiPP natural products that have been vigorously isolated in recent years and is known to possess the extremely rare and highly strained atrop-Trp-Trp linkage. This study details the comprehensive investigation into the construction of the highly strained atrop-Trp-Trp linkage and its application in the total synthesis of strecintide 839.</p></div>","PeriodicalId":74918,"journal":{"name":"Tetrahedron chem","volume":"11 ","pages":"Article 100084"},"PeriodicalIF":0.0000,"publicationDate":"2024-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2666951X24000238/pdfft?md5=030aa36d47ed9088ca853406782b001e&pid=1-s2.0-S2666951X24000238-main.pdf","citationCount":"0","resultStr":"{\"title\":\"Atroposelective total synthesis of strecintide 839\",\"authors\":\"Hiroshige Ogawa, Hugh Nakamura\",\"doi\":\"10.1016/j.tchem.2024.100084\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>The first total synthesis of the recently isolated strecintide 839 is reported. Strecintide 839 is one of the RiPP natural products that have been vigorously isolated in recent years and is known to possess the extremely rare and highly strained atrop-Trp-Trp linkage. This study details the comprehensive investigation into the construction of the highly strained atrop-Trp-Trp linkage and its application in the total synthesis of strecintide 839.</p></div>\",\"PeriodicalId\":74918,\"journal\":{\"name\":\"Tetrahedron chem\",\"volume\":\"11 \",\"pages\":\"Article 100084\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2024-07-10\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.sciencedirect.com/science/article/pii/S2666951X24000238/pdfft?md5=030aa36d47ed9088ca853406782b001e&pid=1-s2.0-S2666951X24000238-main.pdf\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Tetrahedron chem\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2666951X24000238\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Tetrahedron chem","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2666951X24000238","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Atroposelective total synthesis of strecintide 839
The first total synthesis of the recently isolated strecintide 839 is reported. Strecintide 839 is one of the RiPP natural products that have been vigorously isolated in recent years and is known to possess the extremely rare and highly strained atrop-Trp-Trp linkage. This study details the comprehensive investigation into the construction of the highly strained atrop-Trp-Trp linkage and its application in the total synthesis of strecintide 839.