斯特林肽的逆选择全合成 839

Hiroshige Ogawa, Hugh Nakamura
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引用次数: 0

摘要

本研究首次报道了最近分离出的链烯内酯 839 的全合成。链霉内酯 839 是近年来被大力分离的 RiPP 天然产物之一,已知其具有极其罕见的高度紧张的 atrop-Trp-Trp 连接。本研究详细介绍了构建高度紧张的atrop-Trp-Trp连接的综合研究及其在全合成 Strecintide 839 中的应用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Atroposelective total synthesis of strecintide 839

Atroposelective total synthesis of strecintide 839

The first total synthesis of the recently isolated strecintide 839 is reported. Strecintide 839 is one of the RiPP natural products that have been vigorously isolated in recent years and is known to possess the extremely rare and highly strained atrop-Trp-Trp linkage. This study details the comprehensive investigation into the construction of the highly strained atrop-Trp-Trp linkage and its application in the total synthesis of strecintide 839.

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来源期刊
Tetrahedron chem
Tetrahedron chem Organic Chemistry
CiteScore
3.60
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审稿时长
27 days
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