{"title":"对喀麦隆北部用于治疗乳腺癌的植物进行民族药理学调查","authors":"H. Mohamadou , S.R. Tagne , L.L. LIENOU , P.H. Kada , E.E.L. Embolo , K.G. Nganwa , O.J.L. Essame , D.P.M. Jazet","doi":"10.1016/j.hermed.2024.100906","DOIUrl":null,"url":null,"abstract":"<div><h3>Introduction</h3><p>Therapeutic activities of medicinal plants are due to the different secondary metabolites, which are stored in their organs and constitute a large reservoir. These medicinal plants could allow the development of new biomolecules, which would constitute an alternative against highly toxic breast cancer chemotherapy. The present study identifies the medicinal plants used by the traditional medicine practitioners of the northern region of Cameroon in the treatment of this pathology.</p></div><div><h3>Methods</h3><p>A semistructured questionnaire was used to collect sociodemographic information from participants as well as ethnobotanical and ethnopharmacological data of the different treatments. The approach used to conduct the survey was an interview with the traditional medicine practitioners of the region using the local language.</p></div><div><h3>Results</h3><p>As a result, 131 traditional healers were interviewed; they provided 50 therapeutic recipes made from 37 plant species belonging to 21 families. The recipes presented are mainly formulated from a single plant (74%) while among the combinations, associating two plants was predominant (18%). The bark was the most used organ (46%) while the most used preparation methods were decoction (52%) and maceration (36%). Treatments were mainly administered orally for an unlimited duration (until recovery). The plants listed were found to be rich in secondary metabolites such as alkaloids, flavonoids, or tannins that revealed anticancer activities through literature.</p></div><div><h3>Conclusions</h3><p>The results of the present work constitute a strong basis for the search of new anticancer chemotherapeutic agents that would be more available and less invasive.</p></div>","PeriodicalId":56077,"journal":{"name":"Journal of Herbal Medicine","volume":"46 ","pages":"Article 100906"},"PeriodicalIF":2.2000,"publicationDate":"2024-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Ethnopharmacological Investigation of Plants Used in the Treatment of Breast Cancer in Northern Cameroon\",\"authors\":\"H. Mohamadou , S.R. Tagne , L.L. LIENOU , P.H. Kada , E.E.L. Embolo , K.G. Nganwa , O.J.L. Essame , D.P.M. Jazet\",\"doi\":\"10.1016/j.hermed.2024.100906\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Introduction</h3><p>Therapeutic activities of medicinal plants are due to the different secondary metabolites, which are stored in their organs and constitute a large reservoir. These medicinal plants could allow the development of new biomolecules, which would constitute an alternative against highly toxic breast cancer chemotherapy. The present study identifies the medicinal plants used by the traditional medicine practitioners of the northern region of Cameroon in the treatment of this pathology.</p></div><div><h3>Methods</h3><p>A semistructured questionnaire was used to collect sociodemographic information from participants as well as ethnobotanical and ethnopharmacological data of the different treatments. The approach used to conduct the survey was an interview with the traditional medicine practitioners of the region using the local language.</p></div><div><h3>Results</h3><p>As a result, 131 traditional healers were interviewed; they provided 50 therapeutic recipes made from 37 plant species belonging to 21 families. The recipes presented are mainly formulated from a single plant (74%) while among the combinations, associating two plants was predominant (18%). The bark was the most used organ (46%) while the most used preparation methods were decoction (52%) and maceration (36%). Treatments were mainly administered orally for an unlimited duration (until recovery). The plants listed were found to be rich in secondary metabolites such as alkaloids, flavonoids, or tannins that revealed anticancer activities through literature.</p></div><div><h3>Conclusions</h3><p>The results of the present work constitute a strong basis for the search of new anticancer chemotherapeutic agents that would be more available and less invasive.</p></div>\",\"PeriodicalId\":56077,\"journal\":{\"name\":\"Journal of Herbal Medicine\",\"volume\":\"46 \",\"pages\":\"Article 100906\"},\"PeriodicalIF\":2.2000,\"publicationDate\":\"2024-06-26\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Herbal Medicine\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2210803324000630\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"INTEGRATIVE & COMPLEMENTARY MEDICINE\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Herbal Medicine","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2210803324000630","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"INTEGRATIVE & COMPLEMENTARY MEDICINE","Score":null,"Total":0}
Ethnopharmacological Investigation of Plants Used in the Treatment of Breast Cancer in Northern Cameroon
Introduction
Therapeutic activities of medicinal plants are due to the different secondary metabolites, which are stored in their organs and constitute a large reservoir. These medicinal plants could allow the development of new biomolecules, which would constitute an alternative against highly toxic breast cancer chemotherapy. The present study identifies the medicinal plants used by the traditional medicine practitioners of the northern region of Cameroon in the treatment of this pathology.
Methods
A semistructured questionnaire was used to collect sociodemographic information from participants as well as ethnobotanical and ethnopharmacological data of the different treatments. The approach used to conduct the survey was an interview with the traditional medicine practitioners of the region using the local language.
Results
As a result, 131 traditional healers were interviewed; they provided 50 therapeutic recipes made from 37 plant species belonging to 21 families. The recipes presented are mainly formulated from a single plant (74%) while among the combinations, associating two plants was predominant (18%). The bark was the most used organ (46%) while the most used preparation methods were decoction (52%) and maceration (36%). Treatments were mainly administered orally for an unlimited duration (until recovery). The plants listed were found to be rich in secondary metabolites such as alkaloids, flavonoids, or tannins that revealed anticancer activities through literature.
Conclusions
The results of the present work constitute a strong basis for the search of new anticancer chemotherapeutic agents that would be more available and less invasive.
期刊介绍:
The Journal of Herbal Medicine, the official journal of the National Institute of Medical Herbalists, is a peer reviewed journal which aims to serve its readers as an authoritative resource on the profession and practice of herbal medicine. The content areas of the journal reflect the interests of Medical Herbalists and other health professionals interested in the clinical and professional application of botanical medicines. The objective is to strengthen the research and educational base of herbal medicine with research papers in the form of case studies, original research articles and reviews, monographs, clinical trials and relevant in vitro studies. It also publishes policy statements, opinion pieces, book reviews, conference proceedings and profession related information such as pharmacovigilance reports providing an information source for not only the Herbal Practitioner but any Health professional with an interest in phytotherapy.