中毒性表皮坏死症疾病严重程度评分 (SCORTEN) 在小儿史蒂文斯-约翰逊综合征患者中的实用性。

IF 1.5 4区 医学 Q3 CRITICAL CARE MEDICINE
Nina K B Gust, Rebecca M Adams, Ashley Frei, Michelle Coughlin, Justin Klein, Elika Ridelman, Christina Shanti
{"title":"中毒性表皮坏死症疾病严重程度评分 (SCORTEN) 在小儿史蒂文斯-约翰逊综合征患者中的实用性。","authors":"Nina K B Gust, Rebecca M Adams, Ashley Frei, Michelle Coughlin, Justin Klein, Elika Ridelman, Christina Shanti","doi":"10.1093/jbcr/irae140","DOIUrl":null,"url":null,"abstract":"<p><p>The Severity-of-Illness Score for Toxic Epidermal Necrolysis (SCORTEN) is a system that predicts in-hospital mortality for Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis (SJS/TEN). The system is widely utilized in adults but not in pediatrics. We aim to determine the accuracy of the SCORTEN in pediatrics. A retrospective review of pediatric patients admitted to a verified pediatric burn center with SJS/TEN from 2008 to 2022 was performed. Twenty-four patients were analyzed. Ten patients had 0-1 SCORTEN risk factor, 13 had 2 risk factors, and 1 had 3 risk factors. There was no relationship between initial blood urea nitrogen, bicarbonate, glucose, or initial heart rate on the length of an intensive care unit (ICU) stay or ventilator days. Hospital length of stay and feeding tube days were positively related (P < .001) along with length of stay and maximum total body surface areas (P < .05). Hospital length of stay, ICU length of stay, and ventilator days were not statistically significant between those having 0-1 and 2 risk factors. This study suggests that the SCORTEN system is not useful for pediatrics and a different scoring system is needed, as SCORTEN overestimates mortality and does not have a relationship to outcome measures.</p>","PeriodicalId":15205,"journal":{"name":"Journal of Burn Care & Research","volume":" ","pages":"132-137"},"PeriodicalIF":1.5000,"publicationDate":"2025-01-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Utility of the Severity-of-Illness Score for Toxic Epidermal Necrolysis (SCORTEN) in Pediatric Stevens-Johnson Syndrome Patients.\",\"authors\":\"Nina K B Gust, Rebecca M Adams, Ashley Frei, Michelle Coughlin, Justin Klein, Elika Ridelman, Christina Shanti\",\"doi\":\"10.1093/jbcr/irae140\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>The Severity-of-Illness Score for Toxic Epidermal Necrolysis (SCORTEN) is a system that predicts in-hospital mortality for Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis (SJS/TEN). The system is widely utilized in adults but not in pediatrics. We aim to determine the accuracy of the SCORTEN in pediatrics. A retrospective review of pediatric patients admitted to a verified pediatric burn center with SJS/TEN from 2008 to 2022 was performed. Twenty-four patients were analyzed. Ten patients had 0-1 SCORTEN risk factor, 13 had 2 risk factors, and 1 had 3 risk factors. There was no relationship between initial blood urea nitrogen, bicarbonate, glucose, or initial heart rate on the length of an intensive care unit (ICU) stay or ventilator days. Hospital length of stay and feeding tube days were positively related (P < .001) along with length of stay and maximum total body surface areas (P < .05). Hospital length of stay, ICU length of stay, and ventilator days were not statistically significant between those having 0-1 and 2 risk factors. This study suggests that the SCORTEN system is not useful for pediatrics and a different scoring system is needed, as SCORTEN overestimates mortality and does not have a relationship to outcome measures.</p>\",\"PeriodicalId\":15205,\"journal\":{\"name\":\"Journal of Burn Care & Research\",\"volume\":\" \",\"pages\":\"132-137\"},\"PeriodicalIF\":1.5000,\"publicationDate\":\"2025-01-24\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Burn Care & Research\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1093/jbcr/irae140\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"CRITICAL CARE MEDICINE\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Burn Care & Research","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1093/jbcr/irae140","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"CRITICAL CARE MEDICINE","Score":null,"Total":0}
引用次数: 0

摘要

中毒性表皮坏死症疾病严重程度评分(SCORTEN)是一种预测史蒂文斯-约翰逊综合征/中毒性表皮坏死症(SJS/TEN)院内死亡率的系统。该系统广泛用于成人,但未用于儿科。我们旨在确定 SCORTEN 在儿科的准确性。我们对一家经认证的儿科烧伤中心在 2008 年至 2022 年期间收治的 SJS/TEN 儿科患者进行了回顾性分析。对 24 名患者进行了分析。其中,10 名患者有 0-1 个 SCORTEN 危险因素,13 名患者有 2 个危险因素,1 名患者有 3 个危险因素。初始 BUN、碳酸氢盐、血糖或初始心率与重症监护室(ICU)住院时间或呼吸机天数之间没有关系。住院时间和喂食管天数呈正相关(p
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Utility of the Severity-of-Illness Score for Toxic Epidermal Necrolysis (SCORTEN) in Pediatric Stevens-Johnson Syndrome Patients.

The Severity-of-Illness Score for Toxic Epidermal Necrolysis (SCORTEN) is a system that predicts in-hospital mortality for Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis (SJS/TEN). The system is widely utilized in adults but not in pediatrics. We aim to determine the accuracy of the SCORTEN in pediatrics. A retrospective review of pediatric patients admitted to a verified pediatric burn center with SJS/TEN from 2008 to 2022 was performed. Twenty-four patients were analyzed. Ten patients had 0-1 SCORTEN risk factor, 13 had 2 risk factors, and 1 had 3 risk factors. There was no relationship between initial blood urea nitrogen, bicarbonate, glucose, or initial heart rate on the length of an intensive care unit (ICU) stay or ventilator days. Hospital length of stay and feeding tube days were positively related (P < .001) along with length of stay and maximum total body surface areas (P < .05). Hospital length of stay, ICU length of stay, and ventilator days were not statistically significant between those having 0-1 and 2 risk factors. This study suggests that the SCORTEN system is not useful for pediatrics and a different scoring system is needed, as SCORTEN overestimates mortality and does not have a relationship to outcome measures.

求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
CiteScore
2.60
自引率
21.40%
发文量
535
审稿时长
4-8 weeks
期刊介绍: Journal of Burn Care & Research provides the latest information on advances in burn prevention, research, education, delivery of acute care, and research to all members of the burn care team. As the official publication of the American Burn Association, this is the only U.S. journal devoted exclusively to the treatment and research of patients with burns. Original, peer-reviewed articles present the latest information on surgical procedures, acute care, reconstruction, burn prevention, and research and education. Other topics include physical therapy/occupational therapy, nutrition, current events in the evolving healthcare debate, and reports on the newest computer software for diagnostics and treatment. The Journal serves all burn care specialists, from physicians, nurses, and physical and occupational therapists to psychologists, counselors, and researchers.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信