光学显微镜和转录组学揭示胶质瘤手术荧光的起源

IF 26.8 1区医学 Q1 ENGINEERING, BIOMEDICAL

Nature Biomedical Engineering Pub Date : 2024-07-11 DOI:10.1038/s41551-024-01218-2

引用次数: 0

摘要

在胶质瘤手术中，利用荧光引导可增加肿瘤完全切除的机会，同时兼顾神经功能的保护。能对新鲜人脑标本的组织学和荧光成像的多模式光学显微镜揭示了一种意想不到的荧光团聚集模式，以及在手术过程中可视化巨噬细胞的新方法。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Optical microscopy and transcriptomics reveal the origins of fluorescence in glioma surgery

查看原文本刊更多论文

Optical microscopy and transcriptomics reveal the origins of fluorescence in glioma surgery

Fluorescence guidance is utilized to increase the chances of complete tumour resection while balancing preservation of neurological function in glioma surgery. A multimodal optical microscope capable of imaging the histology and fluorescence of fresh human brain specimens revealed an unexpected pattern of fluorophore accumulation and a new means of visualizing macrophages during surgery.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Nature Biomedical Engineering Medicine-Medicine (miscellaneous)

CiteScore

45.30

自引率

1.10%

发文量

138

期刊介绍： Nature Biomedical Engineering is an online-only monthly journal that was launched in January 2017. It aims to publish original research, reviews, and commentary focusing on applied biomedicine and health technology. The journal targets a diverse audience, including life scientists who are involved in developing experimental or computational systems and methods to enhance our understanding of human physiology. It also covers biomedical researchers and engineers who are engaged in designing or optimizing therapies, assays, devices, or procedures for diagnosing or treating diseases. Additionally, clinicians, who make use of research outputs to evaluate patient health or administer therapy in various clinical settings and healthcare contexts, are also part of the target audience.