含有 nheA、hblC 和 cytk 肠毒素基因的蜡样芽孢杆菌与尼日利亚儿童急性肠胃炎有关。

IF 1.4 4区医学 Q4 IMMUNOLOGY

Indian Journal of Medical Microbiology Pub Date : 2024-07-10 DOI:10.1016/j.ijmmb.2024.100666

Ebuka E. David , Ikechuku O. Igwenyi , Ifeanyichukwu R. Iroha , Layla F. Martins , Guillermo Uceda-Campos , Aline M. da Silva

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引用次数: 0

摘要

在发展中国家，由于缺乏鉴定蜡样芽孢杆菌肠毒性基因的分子方法，因此在诊断儿童腹泻病例时很少涉及蜡样芽孢杆菌。我们报告说，在从尼日利亚埃邦伊州 Mile 4 医院住院儿童的 70 份粪便样本中分离出的 62 个肠杆菌中，有 24 个根据 16SrRNA 基因序列被鉴定为蜡样芽孢杆菌。24 个分离株中有 23 个检测到肠毒素基因 nheA 和 cytK2，19 个分离株检测到 hblC。蜡样芽孢杆菌可能是造成尼日利亚儿童急性肠胃炎年发病率较高的原因。

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Bacillus cereus containing nheA, hblC and cytk enterotoxin genes is associated with acute childhood gastroenteritis in Nigeria

Bacillus cereus is rarely implicated when diarrheal cases in children are diagnosed in developing countries due to the lack of molecular methods to identify its enterotoxigenic genes. We report that out of 62 enterobacteria isolated from 70 stool samples collected from children hospitalized at the Mile 4 Hospital, Ebonyi State, Nigeria, 24 isolates were identified as B. cereus based on 16SrRNA gene sequence. The enterotoxins genes nheA and cytK2 were detected in 23 out of the 24 isolates, while hblC was detected in 19 isolates. B. cereus may be responsible for greater number of yearly incidences of acute childhood gastroenteritis in Nigeria.

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来源期刊

Indian Journal of Medical Microbiology IMMUNOLOGY-

CiteScore

2.20

自引率

0.00%

发文量

154

审稿时长

73 days

期刊介绍： Manuscripts of high standard in the form of original research, multicentric studies, meta analysis, are accepted. Current reports can be submitted as brief communications. Case reports must include review of current literature, clinical details, outcome and follow up. Letters to the editor must be a comment on or pertain to a manuscript already published in the IJMM or in relation to preliminary communication of a larger study. Review articles, Special Articles or Guest Editorials are accepted on invitation.