呼吸与绽放肠道缺氧限制白僵菌生长

IF 20.6 1区医学 Q1 MICROBIOLOGY

Cell host & microbe Pub Date : 2024-07-10 DOI:10.1016/j.chom.2024.06.006

Animesh A. Mishra, Andrew Y. Koh

引用次数: 0

摘要

多种宿主和微生物因素决定了白色念珠菌能否在哺乳动物胃肠道定植。在本期《细胞宿主与amp; 微生物》（Cell Host & Microbe）杂志上，Savage 等人证明，恢复肠上皮细胞缺氧足以恢复白色念珠菌的定植抵抗力，即使在其他抑制念珠菌的效应因子仍然耗竭的情况下也是如此。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Breathe and bloom: Gut hypoxia limits C. albicans growth

Multiple host and microbial factors dictate whether Candida albicans can colonize the mammalian gastrointestinal tract. In this issue of Cell Host & Microbe, Savage et al. demonstrate that restoration of intestinal epithelial hypoxia is sufficient to restore Candida albicans colonization resistance, even when other Candida inhibitory effectors remain depleted.

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来源期刊

Cell host & microbe 生物-微生物学

CiteScore

45.10

自引率

1.70%

发文量

201

审稿时长

4-8 weeks

期刊介绍： Cell Host & Microbe is a scientific journal that was launched in March 2007. The journal aims to provide a platform for scientists to exchange ideas and concepts related to the study of microbes and their interaction with host organisms at a molecular, cellular, and immune level. It publishes novel findings on a wide range of microorganisms including bacteria, fungi, parasites, and viruses. The journal focuses on the interface between the microbe and its host, whether the host is a vertebrate, invertebrate, or plant, and whether the microbe is pathogenic, non-pathogenic, or commensal. The integrated study of microbes and their interactions with each other, their host, and the cellular environment they inhabit is a unifying theme of the journal. The published work in Cell Host & Microbe is expected to be of exceptional significance within its field and also of interest to researchers in other areas. In addition to primary research articles, the journal features expert analysis, commentary, and reviews on current topics of interest in the field.