过渡金属催化的涉及内部炔烃的双 C-H 活化/嵌合反应。

IF 7 2区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Chemical record Pub Date : 2024-07-10 DOI:10.1002/tcr.202400069

Fatemeh Doraghi, Mohammad Sadegh Karimtabar, Mehran Ghasemi, Bagher Larijani, Mohammad Mahdavi

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引用次数: 0

摘要

最近，过渡金属催化的涉及两个内部炔烃分子的正交-C-H 键活化/嵌合反应已被广泛用于合成高取代的多环芳烃支架。此类反应已成为组装多功能生物活性分子的强大原子和步骤经济策略。在此背景下，我们重点研究了双 C-H 键活化/annulations 以及涉及二芳基/烷基炔的功能化反应的最新成果。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Transition Metal-Catalyzed Dual C−H Activation/Annulation Reactions Involving Internal Alkynes

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Transition Metal-Catalyzed Dual C−H Activation/Annulation Reactions Involving Internal Alkynes

Recently, transition metal-catalyzed ortho-C−H bond activation/annulations involving two internal alkyne molecules have been extensively used to synthesize highly substituted polycyclic aromatic scaffolds. Such reactions have emerged as a powerful atom and step-economical strategy for the assembly of multifunctional bioactive molecules. In this context, we focused on the recent achievements of dual C−H bond activation/annulations, as well as functionalization reactions involving diaryl/alkyl alkynes.

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来源期刊

Chemical record 化学-化学综合

CiteScore

11.00

自引率

3.00%

发文量

188

审稿时长

>12 weeks

期刊介绍： The Chemical Record (TCR) is a "highlights" journal publishing timely and critical overviews of new developments at the cutting edge of chemistry of interest to a wide audience of chemists (2013 journal impact factor: 5.577). The scope of published reviews includes all areas related to physical chemistry, analytical chemistry, inorganic chemistry, organic chemistry, polymer chemistry, materials chemistry, bioorganic chemistry, biochemistry, biotechnology and medicinal chemistry as well as interdisciplinary fields. TCR provides carefully selected highlight papers by leading researchers that introduce the author''s own experimental and theoretical results in a framework designed to establish perspectives with earlier and contemporary work and provide a critical review of the present state of the subject. The articles are intended to present concise evaluations of current trends in chemistry research to help chemists gain useful insights into fields outside their specialization and provide experts with summaries of recent key developments.